ArticlePloS one2023
Associations between mortality from COVID-19 and other causes: A state-level analysis.
Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed.
- Association of COVID-19 with risks of all-cause and cause-specific mortality post-infection: A UK Biobank cohort study.New microbes and new infections · 2026Article
- Trends in both Alzheimer's disease and Diabetes mellitus related mortality among middle-aged and older adults in the United States, 1999 to 2023: a CDC WONDER database analysis.BMC neurology · 2026Article
- Integrated bioinformatics analysis of the shared molecular mechanisms between Parkinson's disease and COVID-19.mSphere · 2026Article
- Applying machine learning to identify unrecognized COVID-19 deaths recorded as other causes of death in the United States.Science advances · 2026Article
- Brief Report: State Policy Contexts and Disability Risks Among Midlife Working-Age Latino Adults in the U.S.: Variation by Nativity and Citizenship Status.Population research and policy review · 2026Article
- COVID-19 disrupted patterns of cause-specific mortality in Switzerland.International journal of public health · 2026Article
- Trends and Disparities in Mortality due to Diabetes Mellitus and Sepsis in the US Adults: 1999-2023.Endocrinology, diabetes & metabolism · 2025Article
- US-born and foreign-born life expectancy by race and Hispanic origin before and during the COVID-19 pandemic in the United States.Social science & medicine (1982) · 2025Article
- Indirect effects of the COVID-19 pandemic: A cause-of-death analysis of life expectancy changes in 24 countries, 2015 to 2022.PNAS nexus · 2025Article
- Excess natural-cause mortality in US counties and its association with reported COVID-19 deaths.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Trends in sepsis-associated cardiovascular disease mortality in the United States, 1999 to 2022.Frontiers in cardiovascular medicine · 2024Article
- COVID-19 and All-Cause Mortality by Race, Ethnicity, and Age Across Five Periods of the Pandemic in the United States.Population research and policy review · 2023Article
- Immigrant mortality advantage in the United States during the first year of the COVID-19 pandemic.Demographic researchArticle
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5 authors.
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Abstract
backgroundDuring the COVID-19 pandemic, the high death toll from COVID-19 was accompanied by a rise in mortality from other causes of death. The objective of this study was to identify the relationship between mortality from COVID-19 and changes in mortality from specific causes of death by exploiting spatial variation in these relationships across US states.
methodsWe use cause-specific mortality data from CDC Wonder and population estimates from the US Census Bureau to examine relationships at the state level between mortality from COVID-19 and changes in mortality from other causes of death. We calculate age-standardized death rates (ASDR) for three age groups, nine underlying causes of death, and all 50 states and the District of Columbia between the first full year of the pandemic (March 2020-February 2021) and the year prior (March 2019-February 2020). We then estimate the relationship between changes in cause-specific ASDR and COVID-19 ASDR using linear regression analysis weighted by the size of the state's population.
resultsWe estimate that causes of death other than COVID-19 represent 19.6% of the total mortality burden associated with COVID-19 during the first year of the COVID-19 pandemic. At ages 25+, circulatory disease accounted for 51.3% of this burden while dementia (16.4%), other respiratory diseases (12.4%), influenza/pneumonia (8.7%) and diabetes (8.6%) also contribute. In contrast, there was an inverse association across states between COVID-19 death rates and changes in death rates from cancer. We found no state-level association between COVID-19 mortality and rising mortality from external causes.
conclusionsStates with unusually high death rates from COVID-19 experienced an even larger mortality burden than implied by those rates alone. Circulatory disease served as the most important route through which COVID-19 mortality affected death rates from other causes of death. Dementia and other respiratory diseases made the second and third largest contributions. In contrast, mortality from neoplasms tended to decline in states with the highest death rates from COVID-19. Such information may help to inform state-level responses aimed at easing the full mortality burden of the COVID-19 pandemic.
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