Evidence map›Paper›PMID 36877269›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2023

Morus alba: a comprehensive phytochemical and pharmacological review.

Gaber El-Saber Batiha, Ali Esmail Al-Snafi, Mahdi M Thuwaini, John Oluwafemi Teibo, Hazem M Shaheen, Ayomide Peter Akomolafe, Titilade Kehinde Ayandeyi Teibo, Hayder M Al-Kuraishy, Ali I Al-Garbeeb, Athanasios Alexiou and 1 more

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07494253 (Effects of Mulberry Leaf Extract Formulation on Postprandial Glycemic Levels in Obese Children and Adolescents), which is not on this map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07494253 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Effects of Mulberry Leaf Extract Formulation on Postprandial Glycemic Levels in Obese Children and Adolescents: A Pilot Study (PEDRED)

TypeinterventionalSponsorUniversity of Bari Aldo MoroRan2025 to 2026Enrolled80ConditionsObesityArmsReducose, Placebo
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 88 citations in OpenAlex.

  1. Cyclomulberrin fromRSC advances · 2026
    Article
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  3. Review
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  13. Protective Role ofMicroorganisms · 2025
    Article
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  16. Exploring the therapeutic potential of extract in targeting localized adiposity.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2025
    Article
  17. Article
  18. Influence ofBiology · 2025
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 5 countries.

Gaber El-Saber BatihaDepartment of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, 22511, El Beheira, Egypt. gaberbatiha@gmail.com.
Ali Esmail Al-SnafiDepartment of Pharmacology, College of Medicine, University of Thi-Qar, Nasiriyah, Iraq.
Mahdi M ThuwainiCollege of Medical and Healthy Techniques, Southern Technique University, Basra, Iraq.
John Oluwafemi TeiboDepartment of Biochemistry and Immunology, Ribeirão, Preto Medical School , University of São Paulo, Ribeirão Preto, São Paulo, Brazil. johnteibo@usp.br.
Hazem M ShaheenDepartment of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, 22511, El Beheira, Egypt.
Ayomide Peter AkomolafeDepartment of Biochemistry, University of Ibadan, Ibadan, Nigeria.
Titilade Kehinde Ayandeyi TeiboDepartment of Maternal-Infant and Public Health Nursing, College of Nursing, University of São Paulo, Ribeirão PretoRibeirão Preto, São Paulo, Brazil.
Hayder M Al-KuraishyDepartment of Clinical Pharmacologyand, Therapeutic Medicine, College of Medicine , Almustansiriyah University, Baghdad, Iraq.
Ali I Al-GarbeebDepartment of Clinical Pharmacologyand, Therapeutic Medicine, College of Medicine , Almustansiriyah University, Baghdad, Iraq.
Athanasios AlexiouDepartment of Science and Engineering, Novel Global Community Educational Foundation, Hebersham, NSW, 2770, Australia.
Marios PapadakisDepartment of Surgery II, University Hospital Witten-Herdecke, University of Witten-Herdecke, Heusnerstrasse 40, 42283, Wuppertal, Germany. marios_papadakis@yahoo.gr.
Alsalam University College · IQDamanhour University · EGSouthern Technical University · IQThi Qar University · IQUniversidade de Ribeirão Preto · BRUniversidade de São Paulo · BRUniversity of Ibadan · NGWitten/Herdecke University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Morus alba is a fast-growing shrub or medium-sized tree with a straight, cylindrical trunk. Medicinally, whole plants, leaves, fruits, branches, and roots have been employed. Google Scholar, PubMed, Scopus, and Web of Science were used to search for relevant material on the phytochemical components and pharmacologic and mechanism of action of the Morus alba. This was reviewed to assess important updates about Morus alba. The fruits of Morus alba have traditionally been used as an analgesic, anthelmintic, antibacterial, anti-rheumatic, diuretic, hypotensive, hypoglycemia, purgative, restorative, sedative tonic, and blood stimulant. Various plant parts were used as a cooling, sedating, diuretic, tonic, and astringent agent to treat nerve disorders. The plant contained tannins, steroids, phytosterols, sitosterol, glycosides, alkaloids, carbohydrates, proteins, and amino acids, as well as saponins, triterpenes, phenolics, flavonoids, benzofuran derivatives, anthocyanins, anthraquinones, glycosides, vitamins, and minerals. Previous pharmacological research identified antimicrobial, anti-inflammatory, immunological, analgesic, antipyretic, antioxidant, anti-cancer, antidiabetic, gastrointestinal, respiratory, cardiovascular, hypolipidemic, anti-obesity, dermatological, neurological, muscular, and protecting effects. This study looked at Morus alba's traditional uses, chemical components, and pharmacological effects.

Indexed as

AlkaloidsAnti-Infective AgentsAnthocyaninsCaffeineMorusPhytochemicalsPlant ExtractsAlkaloidsAnthocyaninsAnti-Infective AgentsCaffeinePhytochemicalsPlant ExtractsMorus albaPharmacological effectsPhytochemicalsTraditional uses

Identifiers

PMID36877269
PMCPMC10244279
OpenAlexW4323295514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.