ArticleInternational archives of occupational and environmental health2023
Evaluation of long-term data on surface contamination by antineoplastic drugs in pharmacies.
Article in International archives of occupational and environmental health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 10 citations in OpenAlex.
- Development and application of a wipe sampling method for detection of antibiotic surface contamination in hospital wards.Annals of work exposures and health · 2026Article
- Surface Wipe Sampling of Hazardous Medicinal Products: A European Interlaboratory Comparison Study.Drug testing and analysis · 2025Article
- Application of a multifunctional chemotherapy infusion device for reducing antineoplastic drug extravasation.Frontiers in oncology · 2025Article
- Canadian Monitoring Program for Surface Contamination with 11 Antineoplastic Drugs in 126 Centres: Results for 2023.The Canadian journal of hospital pharmacy · 2025Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe handling of antineoplastic drugs represents an occupational health risk for employees in pharmacies. To minimize exposure and to evaluate cleaning efficacy, wipe sampling was used to analyze antineoplastic drugs on surfaces. In 2009, guidance values were suggested to facilitate the interpretation of results, leading to a decrease in surface contamination. The goal of this follow-up was to evaluate the time trend of surface contamination, to identify critical antineoplastic drugs and sampling locations and to reassess guidance values.
methodsPlatinum, 5-fluorouracil, cyclophosphamide, ifosfamide, gemcitabine, methotrexate, docetaxel and paclitaxel were analyzed in more than 17,000 wipe samples from 2000 to 2021. Statistical analysis was performed to describe and interpret the data.
resultsSurface contaminations were generally relatively low. The median concentration for most antineoplastic drugs was below the limit of detection except for platinum (0.3 pg/cm
conclusionOverall, the surface contaminations with antineoplastic drugs continue to decrease or were generally at a low level. Therefore, we adjusted guidance values according to the available data. The identification of critical sampling locations may help pharmacies to further improve cleaning procedure and reduce the risk of occupational exposure to antineoplastic drugs.
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Registered trials
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