Evidence map›Paper›PMID 36877235›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2023

First-in-human imaging using [

Yong Du, Jennifer M Coughlin, Mary Katherine Brosnan, Allen Chen, Laura K Shinehouse, Rehab Abdallah, Martin A Lodge, William B Mathews, Chen Liu, Yunkou Wu and 7 more

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Development and evaluation of deuterated [EJNMMI radiopharmacy and chemistry · 2024
    Article
  6. Review
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Yong DuRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 601 N. Caroline St., JHOC 3223, Baltimore, MD, 21287, USA.
Jennifer M CoughlinDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins Medical Institutions, Baltimore, MD, 21287, USA.
Mary Katherine BrosnanRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 601 N. Caroline St., JHOC 3223, Baltimore, MD, 21287, USA.
Allen ChenRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 601 N. Caroline St., JHOC 3223, Baltimore, MD, 21287, USA.
Laura K ShinehouseRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 601 N. Caroline St., JHOC 3223, Baltimore, MD, 21287, USA.
Rehab AbdallahRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 601 N. Caroline St., JHOC 3223, Baltimore, MD, 21287, USA.
Martin A LodgeRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 601 N. Caroline St., JHOC 3223, Baltimore, MD, 21287, USA.
William B MathewsRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 601 N. Caroline St., JHOC 3223, Baltimore, MD, 21287, USA.
Chen LiuRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 601 N. Caroline St., JHOC 3223, Baltimore, MD, 21287, USA.
Yunkou WuRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 601 N. Caroline St., JHOC 3223, Baltimore, MD, 21287, USA.
Il MinnRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 601 N. Caroline St., JHOC 3223, Baltimore, MD, 21287, USA.
Paige FinleyRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 601 N. Caroline St., JHOC 3223, Baltimore, MD, 21287, USA.
Andrew W HallRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 601 N. Caroline St., JHOC 3223, Baltimore, MD, 21287, USA.
Wojciech G LesniakRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 601 N. Caroline St., JHOC 3223, Baltimore, MD, 21287, USA.
Robert F DannalsRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 601 N. Caroline St., JHOC 3223, Baltimore, MD, 21287, USA.
Andrew G HortiRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 601 N. Caroline St., JHOC 3223, Baltimore, MD, 21287, USA.
Martin G PomperRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 601 N. Caroline St., JHOC 3223, Baltimore, MD, 21287, USA. mpomper@jhmi.edu.ORCID 0000-0001-6753-3010
Johns Hopkins University · US

Funding

Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
Training/Dissemination-Resource for Molecular Imaging Agents in Precision MedicineP41EB024495 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI MARTIN G POMPER · 2017 to 2026
$11.8M
NCATS NIH HHS UL1TR001079NIBIB NIH HHS EB024495
6 · The paper itself

Abstract

purposeWe report findings from the first-in-human study of [

methodsTen healthy adults were imaged according to a 90-min dynamic PET protocol after bolus intravenous injection of [

results[

conclusionThese data demonstrate the safety and pharmacokinetic behavior of [

Indexed as

Positron Emission Tomography Computed TomographyRadiopharmaceuticalsAdultAnimalsBrainCadaverineHumansMicePositron-Emission TomographyReceptors, CannabinoidReproducibility of ResultsCadaverinemonodansylthiacadaverineRadiopharmaceuticalsReceptors, CannabinoidCannabinoid receptor type 2DosimetryHumanPharmacokineticPositron emission tomography

Identifiers

PMID36877235
OpenAlexW4323294329

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.