Evidence map›Paper›PMID 36877026›Full record

ArticleAntimicrobial agents and chemotherapy2023

Combinations of Daptomycin plus Ceftriaxone, but Not Ascending Daptomycin Dose-Regimens, Are Effective in Experimental Endocarditis Caused by Streptococcus mitis

Nagendra N Mishra, Wessam Abdelhady, Ahmed M Elsayed, Christian Lapitan, Richard A Proctor, Michael J Rybak, Jose M Miro, Arnold S Bayer

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Membrane Phenotypic, Metabolic and Genotypic Adaptations ofAntibiotics (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Nagendra N MishraDivision of Infectious Diseases, The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, California, USA.ORCID 0000-0002-7475-5794
Wessam AbdelhadyDivision of Infectious Diseases, The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, California, USA.
Ahmed M ElsayedDivision of Infectious Diseases, The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, California, USA.
Christian LapitanDivision of Infectious Diseases, The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, California, USA.
Richard A ProctorDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Michael J RybakAnti-Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Detroit, Michigan, USA.ORCID 0000-0003-2220-0081
Jose M MiroHospital Clinic, Institut d' Investigacions Biomèdiques August Pi, iSunyer, University of Barcelona, Barcelona, Spain.
Arnold S BayerDivision of Infectious Diseases, The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, California, USA.
UCLA Medical Center · USUniversity of California, Los Angeles · USEugene Applebaum College of Pharmacy and Health Sciences · USInstituto de Salud Carlos III · ESUniversity of Wisconsin–Madison · US

Funding

Mechanisms and Circumvention of Daptomycin Resistance in Streptococcus mitisR01AI130056 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI BAYER, ARNOLD S · 2018 to 2022
$2.4M
A Pharmacologic Approach to Prevent Daptomycin Resistance in VRER01AI121400 · NIAID · WAYNE STATE UNIVERSITY · PI RYBAK, MICHAEL JOSEPH · 2016 to 2020
$1.9M
NIAID NIH HHS R01 AI121400NIAID NIH HHS R01 AI130056
6 · The paper itself

Abstract

The Streptococcus mitis

Indexed as

DaptomycinEndocarditisEndocarditis, BacterialAnimalsAnti-Bacterial AgentsCeftriaxoneHumansMicrobial Sensitivity TestsRabbitsStreptococcus mitisStreptococcus oralisAnti-Bacterial AgentsCeftriaxoneDaptomycinceftriaxonedaptomycinendocarditisS. mitis-oralis

Identifiers

PMID36877026
PMCPMC10112159
OpenAlexW4323293872

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.