Evidence map›Paper›PMID 36876906›Full record

ArticleeLife2023

Identification of a weight loss-associated causal eQTL in

Mi Huang, Daniel Coral, Hamidreza Ardalani, Peter Spegel, Alham Saadat, Melina Claussnitzer, Hindrik Mulder, Paul W Franks, Sebastian Kalamajski

Open access · goldFull text read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Molecular Effects of Physical Activity and Body Composition: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2025
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Mi HuangGenetic and Molecular Epidemiology Unit, Department of Clinical Sciences, Clinical Research Centre, Lund University, Malmö, Sweden.ORCID 0000-0001-6938-5322
Daniel CoralGenetic and Molecular Epidemiology Unit, Department of Clinical Sciences, Clinical Research Centre, Lund University, Malmö, Sweden.
Hamidreza ArdalaniDepartment of Chemistry, Centre for Analysis and Synthesis, Lund University, Lund, Sweden.
Peter SpegelDepartment of Chemistry, Centre for Analysis and Synthesis, Lund University, Lund, Sweden.
Alham SaadatMetabolism Program, Broad Institute of MIT and Harvard, Cambridge, United States.
Melina ClaussnitzerMetabolism Program, Broad Institute of MIT and Harvard, Cambridge, United States.
Hindrik MulderUnit of Molecular Metabolism, Department of Clinical Sciences, Clinical Research Centre, Lund University, Malmö, Sweden.ORCID 0000-0002-6593-8417
Paul W Franks *Genetic and Molecular Epidemiology Unit, Department of Clinical Sciences, Clinical Research Centre, Lund University, Malmö, Sweden.
Sebastian Kalamajski *Genetic and Molecular Epidemiology Unit, Department of Clinical Sciences, Clinical Research Centre, Lund University, Malmö, Sweden.ORCID 0000-0002-6600-9302
Lund University · SEBroad Institute · USHarvard University · US

Funding

European Research Council ERC-2015-CoG -681742 NASCENT
6 · The paper itself

Abstract

Genetic variation at the

Indexed as

AdipocytesObesityCausalityCell LineCRISPR-Cas SystemsEukaryotic Initiation FactorsHumansMitochondrial ProteinsWeight LossEukaryotic Initiation FactorsMitochondrial ProteinsMTIF3 protein, humanadipocytecell biologyCRISPReQTLgeneticsgenomicshumanobesity

Identifiers

PMID36876906
PMCPMC10023155
OpenAlexW4323294232

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read61
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.