Evidence map›Paper›PMID 36876296›Full record

ArticleFASEB bioAdvances2023

Analyzing the interactome of human CK2β in prostate carcinoma cells reveals HSP70-1 and Rho guanin nucleotide exchange factor 12 as novel interaction partners.

Anna Nickelsen, Claudia Götz, Florian Lenz, Karsten Niefind, Simone König, Joachim Jose

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FASEB bioAdvances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Anna NickelsenInstitute of Pharmaceutical and Medicinal Chemistry University of Münster Münster Germany.ORCID https://orcid.org/0000-0001-9887-6403
Claudia GötzDepartment of Medical Biochemistry and Molecular Biology Saarland University Homburg Germany.ORCID https://orcid.org/0000-0001-7115-0485
Florian LenzInstitute of Pharmaceutical and Medicinal Chemistry University of Münster Münster Germany.
Karsten NiefindDepartment of Chemistry, Institute of Biochemistry University of Cologne Köln Germany.ORCID https://orcid.org/0000-0002-0183-6315
Simone KönigInterdisciplinary Center for Clinical Research, Core Unit Proteomics, Medical Faculty University of Münster Münster Germany.ORCID https://orcid.org/0000-0003-0672-7246
Joachim JoseInstitute of Pharmaceutical and Medicinal Chemistry University of Münster Münster Germany.ORCID https://orcid.org/0000-0002-0666-2676
University of Münster · DESaarland University · DEUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CK2β is the non-catalytic modulating part of the S/T-protein kinase CK2. However, the overall function of CK2β is poorly understood. Here, we report on the identification of 38 new interaction partners of the human CK2β from lysates of DU145 prostate cancer cells using photo-crosslinking and mass spectrometry, whereby HSP70-1 was identified with high abundance. The K

Indexed as

HSP70‐1photo‐crosslinking mass spectrometryprostate cancerprotein kinase CK2Rho guanin nucleotide exchange factor 12

Identifiers

PMID36876296
PMCPMC9983076
OpenAlexW4319830320

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.