The relationship between diurnal cortisol slope and cognitive development among children maltreated as infants.

Jane Jiyoun Lee, Eirini Flouri

Abstract read

In one paragraph

Article in Children and youth services review, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jane Jiyoun LeeChild Maltreatment Solutions Network, Social Science Research Institute, Pennsylvania State University, 202 Henderson Building, University Park, PA, 16802.

Eirini FlouriDepartment of Psychology and Human Development, UCL Institute of Education, University College London, 20 Bedford, Way, London, WC1H 0AL.

Funding

Creating the Next Generation of Scholars in CM Science (CMT32)T32HD101390 · NICHD · PENNSYLVANIA STATE UNIVERSITY, THE · PI Erika Lunkenheimer, Hannah Milena Caroline Schreier · 2020 to 2026

$1.9M

NICHD NIH HHS T32 HD101390

6 · The paper itself

Abstract

Little is known about the role of hypothalamic-pituitary-adrenal (HPA) axis functioning for children's cognitive development, especially among vulnerable groups. The current study explores the relationship between diurnal cortisol slope and cognitive outcomes among children at the ages of 5 and 6 who have been maltreated as infants and involved with child protective services, using data from the National Survey of Child and Adolescent Well-Being (NSCAW) I (N=158). Multiple regression analyses showed that a greater decline in salivary cortisol from morning to evening was positively associated with scores on applied problems and expressive communication, even after adjustment for confounding. It was also associated with lower odds of cognitive disability. There were null associations with letter-word identification, passage comprehension, auditory comprehension, matrices, and vocabulary. Results suggest that children involved with child protective services as infants, and thus exposed early to likely 'toxic' levels of stressors, may face dysregulation of the HPA axis and particular difficulties in some aspects of cognitive function. Potential explanations and implications for policy are discussed.

Indexed as

child maltreatmentcognitive developmentNSCAWsalivary cortisoltoxic stress

Identifiers

PMID36876149

DOI10.1016/j.childyouth.2023.106873

PMCPMC9983686

What OpenQuestion holds

Textmetadata

LicenceTDM

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.