Evidence map›Paper›PMID 36875946›Full record

ArticleSudanese journal of paediatrics2022

Pyridoxine in isoniazid-induced psychosis.

Renu Yadav, Manish Kumar, Niraj Kumar, Swathi Chacham

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Sudanese journal of paediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Renu YadavDepartment of Paediatrics, All India Institute of Medical Sciences, Rishikesh, India.
Manish KumarDepartment of Paediatrics, All India Institute of Medical Sciences, Gorakhpur, India.
Niraj KumarDepartment of Neurology, All India Institute of Medical Sciences, Rishikesh, India.
Swathi ChachamDepartment of Paediatrics, All India Institute of Medical Sciences, Rishikesh, India.
All India Institute of Medical Sciences · INAll India Institute of Medical Sciences Rishikesh

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isoniazid is a first-line drug for the management of tuberculosis. Recent changes in paediatric tuberculosis guidelines have insisted on a higher daily dose of isoniazid. Given the burden of paediatric tuberculosis in developing countries, it is pertinent that paediatricians are well versed with all possible adverse effects associated with isoniazid therapy and not just common ones like hepatotoxicity or peripheral neuropathy. Psychosis is one such rare adverse effect which has a reported incidence of 1%-2%. Here, we report a case of isoniazid-induced psychosis in a 4-year-old girl. The purpose of this report is to sensitise the paediatric healthcare community regarding this rare clinical entity along with highlighting the putative role of pyridoxine supplementation in the management of isoniazid-induced psychosis.

Indexed as

isoniazidpsychosispyridoxineTuberculosis

Identifiers

PMID36875946
PMCPMC9983769
OpenAlexW4319157125

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.