ArticleFrontiers in nutrition2023
Extraction, physicochemical properties, and antioxidant activity of natural melanin from
Article in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- Fungal melanin as a bioactive biopolymer: structural diversity, oxidative stress modulation, anticancer mechanisms, and therapeutic perspectives.RSC advances · 2026Review
- Extraction and Purification of a Melanin fromMicroorganisms · 2026Article
- Optimized melanin production from marine-associated Bacillus sp. EGY7 as a sustainable precursor of carbon dots for biomedical applications.Bioresources and bioprocessing · 2026Article
- Analysis of the Subculture Effect on theJournal of fungi (Basel, Switzerland) · 2026Article
- Dismantling darkness: interdisciplinary perspectives on melanin degradation.World journal of microbiology & biotechnology · 2026Review
- Structural Characterization and Stability Evaluation of Melanin fromFoods (Basel, Switzerland) · 2026Article
- Preparation and In Vitro Bioactivity Evaluation ofFoods (Basel, Switzerland) · 2026Article
- Harnessing Edible Insect Bioactives for Gut Health: A Comprehensive Review on Chitin-Derived Prebiotics and Peptidomic Insights from the Black Soldier Fly.Foods (Basel, Switzerland) · 2025Review
- Edible Fungi Melanin: Recent Advances in Extraction, Characterization, Biological Activity and Applications.Journal of fungi (Basel, Switzerland) · 2025Review
- Isolation and Structural Characterization of Melanins from Red and Yellow Varieties ofInternational journal of molecular sciences · 2025Article
- Comparative Genomic Analysis of Two Monokaryons ofJournal of fungi (Basel, Switzerland) · 2025Article
- Melanin inFood science and biotechnology · 2024Review
- Synthesis and structural characteristics analysis of melanin pigments induced by blue light inFrontiers in microbiology · 2023Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Natural melanin from Methods: In this study, single-factor experiments, Box-Behnken design (BBD), and response surface methodology (RSM) were employed to investigate the effects of alkali-soluble pH, acid precipitation pH, and microwave time on the extraction yield of Results: The results showed that alkali-soluble pH, acid precipitation pH, and microwave time significantly affected the AHM yield, with the following optimized microwave-assisted extraction conditions: alkali-soluble pH of 12.3, acid precipitation pH of 3.1, and microwave time of 53 min, resulting in an AHM extraction yield of 0.4042%. AHM exhibited a strong absorption at 210 nm, similar to melanin from other sources. FT-IR spectroscopy also revealed that AHM exhibited the three characteristic absorption peaks of natural melanin. The HPLC chromatogram profile of AHM showed a single symmetrical elution peak with a 2.435 min retention time. AHM was highly soluble in alkali solution, insoluble in distilled water and organic solvents, and demonstrated strong DPPH, OH, and ABTS free radical scavenging activities. Discussion: This study provides technical support to optimize AHM extraction for use in the medical and food industries.
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