Evidence map›Paper›PMID 36875801›Full record

ArticleAddictive behaviors reports2023

Multiple substance use and blood pressure in women experiencing homelessness.

Leslie W Suen, Eric Vittinghoff, Alan H B Wu, Akshay Ravi, Phillip O Coffin, Priscilla Hsue, Kara L Lynch, Dhruv S Kazi, Elise D Riley

Open access · goldAbstract read
In one paragraph

Article in Addictive behaviors reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Housing Instability Associated with Return to Stimulant Use among Previously Abstaining Women.International journal of environmental research and public health · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Leslie W SuenNational Clinician Scholars Program, Philip R. Lee Institute of Health Policy Studies, University of California, San Francisco, San Francisco, CA, United States.
Eric VittinghoffDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, United States.
Alan H B WuDepartment of Laboratory Medicine, University of California, San Francisco, San Francisco, CA, United States.
Akshay RaviDepartment of Medicine, University of California, San Francisco, San Francisco, CA, United States.
Phillip O CoffinDepartment of Medicine, Division of HIV, Infectious Diseases and Global Medicine, School of Medicine, University of California, San Francisco, San Francisco, CA, United States.
Priscilla HsueDivision of Cardiology, Chan Zuckerberg San Francisco General Hospital, San Francisco, CA, United States.
Kara L LynchDepartment of Laboratory Medicine, University of California, San Francisco, San Francisco, CA, United States.
Dhruv S KaziRichard A. and Susan F. Smith Center for Outcomes Research, Beth Israel Deaconess Medical Center, Boston, MA, United States.
Elise D RileyDepartment of Medicine, Division of HIV, Infectious Diseases and Global Medicine, School of Medicine, University of California, San Francisco, San Francisco, CA, United States.
University of California, San Francisco · USBeth Israel Deaconess Medical Center · USSan Francisco General Hospital · USSan Francisco VA Medical Center · US

Funding

Impact of Cocaine and Polydrug Use on Cranial Small Vessel DiseaseR01DA037012 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RILEY, ELISE D. · 2014 to 2018
$4.1M
Cocaine use, viral suppression and precursors of stroke in HIV infectionR01DA049648 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RILEY, ELISE D. · 2020 to 2024
$4.0M
Mentoring patient-oriented research on the health consequences of polydrug useK24DA039780 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RILEY, ELISE D. · 2015 to 2025
$1.9M
Midcareer K24 Award for Mentoring and Patient-Oriented ResearchK24DA042720 · NIDA · SAN FRANCISCO DEPARTMENT OF PUBLIC HEALTH · PI PHILLIP O COFFIN · 2016 to 2026
$1.6M
Enhancing Resident Investigation and Career Advancement in Cardiovascular and Pulmonary ScienceR38HL143581 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BIBBINS-DOMINGO, KIRSTEN, HUANG, ALISON · 2018 to 2021
$1.4M
NHLBI NIH HHS R38 HL143581NIDA NIH HHS K24 DA039780NIDA NIH HHS K24 DA042720NIDA NIH HHS R01 DA037012NIDA NIH HHS R01 DA049648
6 · The paper itself

Abstract

Background: Substance use increases risk of cardiovascular events, particularly among women with additional risk factors like housing instability. While multiple substance use is common among unstably housed individuals, relationships between multiple substance use and cardiovascular risk factors like blood pressure are not well characterized. Methods: We conducted a cohort study between 2016 and 2019 to examine associations between multiple substance use and blood pressure in women experiencing homelessness and unstable housing. Participants completed six monthly visits including vital sign assessment, interview, and blood draw to assess toxicology-confirmed substance use (e.g., cocaine, alcohol, opioids) and cardiovascular health. We used linear mixed models to evaluate the outcomes of systolic and diastolic blood pressure (SBP; DBP). Results: Mean age was 51.6 years; 74 % were women of color. Prevalence of any substance use was 85 %; 63 % of participants used at least two substances at baseline. Adjusting for race, body mass index and cholesterol, cocaine was the only substance significantly associated with SBP (4.71 mmHg higher; 95 % CI 1.68, 7.74) and DBP (2.83 mmHg higher; 95 % CI 0.72, 4.94). Further analysis found no differences in SBP or DBP between those with concurrent use of other stimulants, depressants, or both with cocaine, compared to those who used cocaine only. Conclusions: Cocaine was the only substance associated with higher SBP and DBP, even after accounting for simultaneous use of other substances. Along with interventions to address cocaine use, stimulant use screening during cardiovascular risk assessment and intensive blood pressure management may improve cardiovascular outcomes among women experiencing housing instability.

Indexed as

Blood pressureCocaineHypertensionSubstance-related disordersWomen

Identifiers

PMID36875801
PMCPMC9975611
OpenAlexW4320486853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.