Evidence map›Paper›PMID 36875755›Full record

ArticleFrontiers in cell and developmental biology2023

Deficiency in the cell-adhesion molecule

Manxiu Ma, Alyssa A Brunal, Kareem C Clark, Carleigh Studtmann, Katelyn Stebbins, Shin-Ichi Higashijima, Y Albert Pan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Manxiu MaFralin Biomedical Research Institute at Virginia Tech Carilion, Virginia Tech, Roanoke, VA, United States.
Alyssa A BrunalFralin Biomedical Research Institute at Virginia Tech Carilion, Virginia Tech, Roanoke, VA, United States.
Kareem C ClarkFralin Biomedical Research Institute at Virginia Tech Carilion, Virginia Tech, Roanoke, VA, United States.
Carleigh StudtmannFralin Biomedical Research Institute at Virginia Tech Carilion, Virginia Tech, Roanoke, VA, United States.
Katelyn StebbinsFralin Biomedical Research Institute at Virginia Tech Carilion, Virginia Tech, Roanoke, VA, United States.
Shin-Ichi HigashijimaNational Institutes of Natural Sciences, Exploratory Research Center on Life and Living Systems, National Institute for Basic Biology, Okazaki, Aichi, Japan.
Y Albert PanFralin Biomedical Research Institute at Virginia Tech Carilion, Virginia Tech, Roanoke, VA, United States.
Virginia Tech · USBiomedical Research Institute · USCarilion Clinic · USNational Institutes of Natural Sciences · JP

Funding

Mechanisms and significance of programmed cell death in hypothalamic CRH neuronsR01MH131820 · NIMH · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI YUCHIN Albert Pan · 2023 to 2026
$1.6M
NIMH NIH HHS R01 MH131820
6 · The paper itself

Abstract

The corticotropin-releasing hormone (CRH)-expressing neurons in the hypothalamus are critical regulators of the neuroendocrine stress response pathway, known as the hypothalamic-pituitary-adrenal (HPA) axis. As developmental vulnerabilities of CRH neurons contribute to stress-associated neurological and behavioral dysfunctions, it is critical to identify the mechanisms underlying normal and abnormal CRH neuron development. Using zebrafish, we identified

Indexed as

CRH neurondevelopmentHPA (hypothalamic-pituitary-adrenal) axishypothalamuszebrafish

Identifiers

PMID36875755
PMCPMC9978177
OpenAlexW4321091822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.