Evidence map›Paper›PMID 36875660›Full record

ReviewFrontiers in neuroscience2023

Functional networks in prolonged disorders of consciousness.

Hui Li, Xiaonian Zhang, Xinting Sun, Linghui Dong, Haitao Lu, Shouwei Yue, Hao Zhang

Erratum issued Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06268236 (Electro-acupuncture to Treat Disorder of Consciousness), which is not on this map. Cited by 31 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06268236 narecruitingnot on this mapstarted 2024, after this paper: background citation

Electro-acupuncture to Treat Disorder of Consciousness

TypeinterventionalSponsorThe Second Affiliated Hospital, Guangzhou University of Traditional Chinese MedicineRan2024 to 2026Enrolled50ConditionsDisorder of Consciousness, ElectroacupunctureArmsElectroacupuncture, Sham electroacupuncture
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  10. [Guangdong consensus on integrated Chinese and Western medicine management of prolonged disorders of consciousness].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Hui LiCheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Xiaonian ZhangDepartment of Neurorehabilitation, China Rehabilitation Research Center, Beijing, China.
Xinting SunDepartment of Neurorehabilitation, China Rehabilitation Research Center, Beijing, China.
Linghui DongCheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Haitao LuDepartment of Neurorehabilitation, China Rehabilitation Research Center, Beijing, China.
Shouwei YueCheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Hao ZhangCheeloo College of Medicine, Shandong University, Jinan, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prolonged disorders of consciousness (DoC) are characterized by extended disruptions of brain activities that sustain wakefulness and awareness and are caused by various etiologies. During the past decades, neuroimaging has been a practical method of investigation in basic and clinical research to identify how brain properties interact in different levels of consciousness. Resting-state functional connectivity within and between canonical cortical networks correlates with consciousness by a calculation of the associated temporal blood oxygen level-dependent (BOLD) signal process during functional MRI (fMRI) and reveals the brain function of patients with prolonged DoC. There are certain brain networks including the default mode, dorsal attention, executive control, salience, auditory, visual, and sensorimotor networks that have been reported to be altered in low-level states of consciousness under either pathological or physiological states. Analysis of brain network connections based on functional imaging contributes to more accurate judgments of consciousness level and prognosis at the brain level. In this review, neurobehavioral evaluation of prolonged DoC and the functional connectivity within brain networks based on resting-state fMRI were reviewed to provide reference values for clinical diagnosis and prognostic evaluation.

Indexed as

fMRIfunctional connectivitynetworkneuroimagingprolonged DoC

Identifiers

PMID36875660
PMCPMC9981972

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.