ArticleCritical care explorations2023
Hyperoxemia During Cardiac Surgery Is Associated With Postoperative Pulmonary Complications.
Article in Critical care explorations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 3 citations in OpenAlex.
- Effect of one-lung ventilation in children undergoing lateral thoracotomy cardiac surgery with cardiopulmonary bypass on postoperative atelectasis and postoperative pulmonary complications.BMC pediatrics · 2025Trial
- Association between intraoperative inspired oxygen exposure and risk of postoperative pulmonary complications in abdominal surgery: a multi-center prospective cohort study.Journal of anesthesia · 2026Article
- Incidence and risk factors of hyperoxemia among potentially critically ill patients treated in hospital wards: a retrospective study.Turkish journal of medical sciences · 2025Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
The use of hyperoxemia during cardiac surgery remains controversial. We hypothesized that intraoperative hyperoxemia during cardiac surgery is associated with an increased risk of postoperative pulmonary complications.
designRetrospective cohort study.
settingWe analyzed intraoperative data from five hospitals within the Multicenter Perioperative Outcomes Group between January 1, 2014, and December 31, 2019. We assessed intraoperative oxygenation of adult patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Hyperoxemia pre and post CPB was quantified as the area under the curve (AUC) of Fio PATIENTS: Twenty-one thousand six hundred thirty-two cardiac surgical patients.
interventionsNone. MEASUREMENTS AND MAIN
resultsDuring 21,632 distinct cardiac surgery cases, 96.4% of patients spent at least 1 minute in hyperoxemia (99.1% pre-CPB, 98.5% intra-CPB, and 96.4% post-CPB). Increasing exposure to hyperoxemia was associated with an increased risk of postoperative pulmonary complications throughout three distinct surgical periods. During CPB, increasing exposure to hyperoxemia was associated with an increased odds of developing postoperative pulmonary complications (
conclusionsHyperoxemia occurs almost universally during cardiac surgery. Exposure to hyperoxemia assessed continuously as an AUC during the intraoperative period, but particularly during CPB, was associated with an increased incidence of postoperative pulmonary complications.
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Registered trials
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