Evidence map›Paper›PMID 36875442›Full record

ArticleChinese herbal medicines2023

Comparison of intestinal absorption characteristics between rhubarb traditional Chinese medicine preparation and activity ingredients using

Wenjing Ta, Xiaoying Yang, Jie Wang, Chengkun Han, Ruochen Hua, Wen Lu

Abstract read
In one paragraph

Article in Chinese herbal medicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Colonic Submucosa Targeted Delivery of Probiotic and Rhein for Ulcerative Colitis Treatment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  3. Biopharmaceutical profiling of anti-infective sanggenons fromInternational journal of pharmaceutics: X · 2024
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenjing TaHealth Science Center, School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, China.
Xiaoying YangShaanxi Regional Center, National Anti-Drug Laboratory, Xi'an 710000, China.
Jie WangHealth Science Center, School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, China.
Chengkun HanHealth Science Center, School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, China.
Ruochen HuaHealth Science Center, School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, China.
Wen LuHealth Science Center, School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The intestinal absorption characteristics of active ingredients are very important for oral administration of traditional Chinese medicine (TCM) to achieve the desired therapeutic effect. However, a deeper understanding about active ingredients absorption characteristics is still lack. The aim of this study was to investigate the absorption properties and mechanism of rhubarb active ingredients in TCM preparation and pure form. Methods: The intestinal absorption behavior of active ingredients in Shenkang extract (SKE) and rhubarb anthraquinone ingredients (RAI) were investigated by Results: Conclusion: Four rhubarb anthraquinone ingredients in SKE and RAI have similar absorption mechanism and different absorption behavior, and the microenvironment of the study models influenced their absorption behavior. The results may provide an aid for understanding of the absorption characteristics of the TCM active ingredients in complex environments and the complementarities of different research models.

Indexed as

absorption characteristicsCaco-2 cell monolayer modelrhubarb anthraquinonesingle-pass intestinal perfusion modeltraditional Chinese medicine

Identifiers

PMID36875442
PMCPMC9975633

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.