ArticleFrontiers in public health2023
Global, regional, and national HIV/AIDS disease burden levels and trends in 1990-2019: A systematic analysis for the global burden of disease 2019 study.
Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 5 of them syntheses that pooled it.
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61 citing papers in PubMed, 5 syntheses or guidelines pooled it, 108 citations in OpenAlex.
- Antiretroviral Therapy Adherence Interventions in the Era of Universal Test and Treat: A Hybrid Systematic-Narrative Literature Review of Global Evidence.AIDS and behavior · 2026Pooled it
- Association of HIV infection and hospitalization among mpox cases: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Thyroid disorders in patients with human immunodeficiency virus infection: a meta-analysis.AIDS research and therapy · 2025Pooled it
- Prevalence of HIV in slums area: a systematic review and meta-analysis.BMC infectious diseases · 2024Pooled it
- Acute kidney injury and its predictors among HIV-positive patients in Africa: Systematic review and meta-analysis.PloS one · 2024Pooled it
- Evaluation of the effects of Artemisia Annua L. and Moringa Oleifera Lam. on CD4 count and viral load among PLWH on ART at Mbarara Regional Referral Hospital: a double-blind randomized controlled clinical trial.AIDS research and therapy · 2024Trial
- Integration of specialised mental health services in an HIV clinic in a low resource setting.BMJ open quality · 2026Article
- AI-augmented communication improves HIV PrEP initiation and persistence in populations disproportionately impacted by HIV.NPJ digital medicine · 2026Article
- Comprehensive analysis of spinal cord inflammatory factors in HIV Tat-induced neuropathy in mice.Neuroscience · 2026Article
- Frequency of Intestinal Parasitic Infection and Associated Factors Among HIV Patients on Antiretroviral Therapy at Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia: A 5-Year Retrospective Study.Journal of tropical medicine · 2026Article
- Article
- Survival outcomes and influencing factors in Zhengzhou HIV/AIDS patients following antiretroviral therapy initiation (2014-2024): a retrospective cohort analysis.Frontiers in public health · 2026Article
- An assessment of anxiety and depression among HIV-positive pregnant women in a tertiary hospital located in southeast Nigeria: a cross-sectional comparative analysis.Frontiers in psychiatry · 2026Article
- A Scientometric Mapping of Global Lenacapavir and HIV Research: Dynamism, Visualization, and Emerging Patterns.International journal of preventive medicine · 2026Article
- Medication Adherence and Beliefs about HIV Treatment in Jordan: A Cross-Sectional Analysis.AIDS and behavior · 2025Article
- Disease burden of HIV and its behavioral risks among adults aged 20-54 years in China and the Western Pacific Region from 1990 to 2021: an analysis based on the Global Burden of Disease Study 2021.BMC infectious diseases · 2025Article
- Opportunities and Challenges of Multiomics for Discovery and Monitoring of Human Pathogens.Environment & health (Washington, D.C.) · 2025Review
- Gender equality in leadership of HIV care cascade clinical trials: A methodological study.HIV medicine · 2025Article
- Developing and Validating an Inclusive and Cost-Effective Prediction Algorithm for Survival and Death Among People Living With HIV in Sub-Saharan Africa: Protocol for a Meta-Analysis and Case-Control and Cost-Effectiveness Study.JMIR research protocols · 2025Article
- Proactive recognition and early detection in communities through targeted HIV screening.Scientific reports · 2025Article
1 more citing papers are in PubMed but not listed here.
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9 authors at 4 institutions in 1 country.
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Abstract
Background: Since the first HIV/AIDS case appeared in 1980s, HIV/AIDS has been the focus of international attention. As a major public health problem, there are epidemiological uncertainties about the future of HIV/AIDS. It is important to monitor the global statistics of HIV/AIDS prevalence, deaths, disability adjusted life years (DALYs), and risk factors for adequate prevention and control. Methods: The Global Burden of Disease Study 2019 database was used to analyze the burden of HIV/AIDS in 1990-2019. By extracting global, regional, and national data on HIV/AIDS prevalence, deaths, and DALYs, we described the distribution by age and sex, explored the risk factors, and analyzed the trends in HIV/AIDS. Results: In 2019, there were 36.85 million HIV/AIDS cases (95% UI: 35.15-38.86 million), 863.84 thousand deaths (95% UI: 78.61-99.60 thousand), and 47.63 million (95% UI: 42.63-55.65 million) DALYs. The global age-standardized HIV/AIDS prevalence, death, and DALY rates were 454.32 (95% UI: 433.76-478.59), 10.72 (95% UI: 9.70-12.39), and 601.49 (95% UI: 536.16-703.92) per 100,000 cases, respectively. In 2019, the global age-standardized HIV/AIDS prevalence, death, and DALY rates increased by 307.26 (95% UI: 304.45-312.63), 4.34 (95% UI: 3.78-4.90), and 221.91 (95% UI: 204.36-239.47) per 100,000 cases, respectively, compared to 1990. Age-standardized prevalence, death, and DALY rates decreased in high sociodemographic index (SDI) areas. High age-standardized rates were observed in low sociodemographic index areas, while low age-standardized rates were observed in high sociodemographic index areas. In 2019, the high age-standardized prevalence, death, and DALY rates were predominant in Southern Sub-Saharan Africa, and global DALYs peaked in 2004 and subsequently decreased. The highest global HIV/AIDS DALYs were in the 40-44 age group. The main risk factors affecting HIV/AIDS DALY rates included behavioral risks, drug use, partner violence, and unsafe sex. Conclusions: HIV/AIDS disease burden and risk factors vary by region, sex, and age. As access to health care increases across countries and treatment for HIV/AIDS infection improves, the HIV/AIDS disease burden is concentrated in areas with low SDIs, particularly in South Africa. Regional differences should be fully considered to target optimal prevention strategies and treatment options based on risk factors.
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