Evidence map›Paper›PMID 36875327›Full record

ArticlePhysics and imaging in radiation oncology2023

Implementation of triggered kilovoltage imaging for stereotactic radiotherapy of the spine for patients with spinal fixation hardware.

Ashley J Cetnar, Michael Degnan, Joseph Pichler, Sagarika Jain, Samantha Morelli, Evan Thomas, J Bradley Elder, Thomas J Scharschmidt, Joshua D Palmer, Dukagjin M Blakaj

Abstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ashley J CetnarThe Ohio State University, James Cancer Hospital and Solove Research Institute, Department of Radiation Oncology, 460 W. 10th Ave., Columbus, OH 43210, USA.
Michael DegnanThe Ohio State University, James Cancer Hospital and Solove Research Institute, Department of Radiation Oncology, 460 W. 10th Ave., Columbus, OH 43210, USA.
Joseph PichlerThe Ohio State University, James Cancer Hospital and Solove Research Institute, Department of Radiation Oncology, 460 W. 10th Ave., Columbus, OH 43210, USA.
Sagarika JainThe Ohio State University, James Cancer Hospital and Solove Research Institute, Department of Radiation Oncology, 460 W. 10th Ave., Columbus, OH 43210, USA.
Samantha MorelliThe Ohio State University, James Cancer Hospital and Solove Research Institute, Department of Radiation Oncology, 460 W. 10th Ave., Columbus, OH 43210, USA.
Evan ThomasThe Ohio State University, James Cancer Hospital and Solove Research Institute, Department of Radiation Oncology, 460 W. 10th Ave., Columbus, OH 43210, USA.
J Bradley ElderThe Ohio State University, James Cancer Hospital and Solove Research Institute, Department of Radiation Oncology, 460 W. 10th Ave., Columbus, OH 43210, USA.
Thomas J ScharschmidtThe Ohio State University, James Cancer Hospital and Solove Research Institute, Department of Radiation Oncology, 460 W. 10th Ave., Columbus, OH 43210, USA.
Joshua D PalmerThe Ohio State University, James Cancer Hospital and Solove Research Institute, Department of Radiation Oncology, 460 W. 10th Ave., Columbus, OH 43210, USA.
Dukagjin M BlakajThe Ohio State University, James Cancer Hospital and Solove Research Institute, Department of Radiation Oncology, 460 W. 10th Ave., Columbus, OH 43210, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Mitigation of intrafraction motion (IM) is valuable in stereotactic radiotherapy (SRT) radiotherapy where submillimeter accuracy is desired. The purpose of this study was to investigate the application of triggered kilovoltage (kV) imaging for spine SRT patients with hardware by correlating kV imaging with patient motion and summarizing implications of tolerance for IM based on calculated dose. Materials and methods: Ten plans (33 fractions) were studied, correlating kV imaging during treatment with pre- and post-treatment cone beam computed tomography (CBCT). Images were taken at 20-degree gantry angle intervals during the arc-based treatment. The contour of the hardware with a 1 mm expansion was displayed at the treatment console to manually pause treatment delivery if the hardware was visually detected outside the contour. The treatment CBCTs were compared using retrospective image registration to assess the validity of contour-based method for pausing treatment. Finally, plans were generated to estimate dose volume objective differences in case of 1 mm deviation. Results: When kV imaging during treatment was used with the 1 mm contour, 100 % of the post-treatment CBCTs reported consistent results. One patient in the cohort exhibited motion greater than 1 mm during treatment which allowed intervention and re-setup during treatment. The average translational motion was 0.35 mm. Treatment plan comparison at 1 mm deviation showed little differences in calculated dose for the target and cord. Conclusions: Utilizing kV imaging during treatment is an effective method of assessing IM for SRT spine patients with hardware without increasing treatment time.

Indexed as

Advanced imagingIntrafraction motion reviewSpineStereotacticTriggered imaging

Identifiers

PMID36875327
PMCPMC9978845

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.