ArticleLancet regional health. Americas2023
Impact of social disparities on 10 year survival rates in paediatric cancers: a cohort study.
Article in Lancet regional health. Americas, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 13 citations in OpenAlex.
- A comparative effectiveness trial for universal psychosocial screening with the Psychosocial Assessment Tool (PAT) across 18 childhood cancer programs in the United States: adoption, penetration, and health equity.Implementation science : IS · 2026Trial
- Article
- Area-Based Marginalization and Incidence of Childhood Cancer.JAMA network open · 2026Article
- Cancer survival and its social determinants among children with a migrant background: systematic review protocol.BMJ open · 2026Article
- Associations of Social Deprivation and Oncology Physician Network Vulnerability With Acute Care Utilization in the SEER-Medicare Population.Health services research · 2026Article
- Secondary Neoplasm in Survivors of Childhood Hematological Malignancies-Systematic Review.Children (Basel, Switzerland) · 2026Review
- Practical Considerations for using Social Determinants of Health for Disease Prediction in All of Us.Research square · 2026Article
- Practical considerations for social determinant-based disease prediction in the All of Us research program.Communications health · 2026Article
- Physical Therapy Is an Underutilized Health Resource for Children with Cancer: A Retrospective Study Identifies Facilitators for Improvement.Healthcare (Basel, Switzerland) · 2025Article
- The impact of social determinants of health on outcomes of brexucabtagene autoleucel in adults with relapsed/refractory B-cell acute lymphoblastic leukemia.Bone marrow transplantation · 2025Article
- Area Deprivation and Pediatric Cancer Mortality: An Analysis of 2000 to 2020 State Cancer Registry Data.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025Article
- Article
- Social, Behavioral, and Clinical Risk Factors Are Associated with Clonal Hematopoiesis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024Article
- Association of county level poverty with mortality from primary liver cancers.Cancer medicine · 2024Article
- Novel insights on genetics and epigenetics as clinical targets for paediatric astrocytoma.Clinical and translational medicine · 2024Review
- The most vulnerable pediatric cancer patients.Lancet regional health. Americas · 2023Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Studies reporting on the impact of social determinants of health on childhood cancer are limited. The current study aimed to examine the relationship between health disparities, as measured by the social deprivation index, and mortality in paediatric oncology patients using a population-based national database. Methods: In this cohort study of children across all paediatric cancers, survival rates were determined using the Surveillance, Epidemiology, and End Results (SEER) database from 1975 to 2016. The social deprivation index was used to measure and assess healthcare disparities and specifically the impact on both overall and cancer-specific survival. Hazard ratios were used to assess the association of area deprivation. Findings: The study cohort was composed of 99,542 patients with paediatric cancer. Patients had a median age of 10 years old (IQR: 3-16) with 46,109 (46.3%) of female sex. Based on race, 79,984 (80.4%) of patients were identified as white while 10,801 (10.9%) were identified as Black. Patients from socially deprived areas had significantly higher hazard of death overall for both non-metastatic [1.27 (95% CI: 1.19-1.36)] and metastatic presentations [1.09 (95% CI: 1.05-1.15)] compared to in more socially affluent areas. Interpretation: Patients from the most socially deprived areas had lower rates of overall and cancer-specific survival compared to patients from socially affluent areas. With an increase in childhood cancer survivors, implementation of social determinant indices, such as the social deprivation index, might aid improvement in healthcare outcomes for the most vulnerable patients. Funding: There was no study sponsor or extramural funding.
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