Evidence map›Paper›PMID 36875252›Full record

ArticleCureus2023

Three Patients With Chorea and Positive Voltage-Gated Potassium Channel Antibody: Is This the Link Between Hyperkinetic von Economo Disease and COVID-19?

Jacqueline Dulanto, David Chu, Pardis Saffari, Mina Abdelshahid, Prissilla Xu, Jacob Hauser, Jonathan Eskenazi, Lynnea Morm, Antonio K Liu

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jacqueline DulantoInternal Medicine, Adventist Health White Memorial, Los Angeles, USA.
David ChuInternal Medicine, Adventist Health White Memorial, Los Angeles, USA.
Pardis SaffariInternal Medicine, Adventist Health White Memorial, Los Angeles, USA.
Mina AbdelshahidFamily Medicine, AltaMed Health Services, Los Angeles, USA.
Prissilla XuPharmacy Services, Adventist Health White Memorial, Los Angeles, USA.
Jacob HauserNeurology, Adventist Health White Memorial, Los Angeles, USA.
Jonathan EskenaziNeurology, California Hospital Medical Center, Los Angeles, USA.
Lynnea MormFamily Medicine, AltaMed Health Services, Los Angeles, USA.
Antonio K LiuNeurology, Adventist Health White Memorial, Los Angeles, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chorea, hemichorea, and other movement disorders have been reported after different pandemics since Constantin von Economo's time. In the current COVID-19 pandemic, numerous delayed neurological manifestations have been reported in the postinfectious or postvaccination periods. However, very few of these are movement disorders in nature; there are even fewer voltage-gated potassium channel (VGKC) antibody-related movement disorder cases in the literature. We encountered three patients with some COVID-19-related issues featuring both chorea and VGKC antibody. Modern medical science and technology may be able to further our understanding of the molecular basis of von Economo disease and reveal a possible link to COVID-19 along with the immunomodulation aspect of its treatment.

Indexed as

choreacovid-19postinfectiousvoltage-gated potassium channel antibodyvon economo disease

Identifiers

PMID36875252
PMCPMC9981230

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.