Evidence map›Paper›PMID 36875239›Full record

ArticleFrontiers in human neuroscience2023

The effects of white matter hyperintensities on MEG power spectra in population with mild cognitive impairment.

Lucia Torres-Simon, Pablo Cuesta, Alberto Del Cerro-Leon, Brenda Chino, Lucia H Orozco, Elisabeth B Marsh, Pedro Gil, Fernando Maestu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Lucia Torres-SimonCenter of Cognitive and Computational Neuroscience, Universidad Complutense de Madrid (UCM), Madrid, Spain.
Pablo CuestaCenter of Cognitive and Computational Neuroscience, Universidad Complutense de Madrid (UCM), Madrid, Spain.
Alberto Del Cerro-LeonCenter of Cognitive and Computational Neuroscience, Universidad Complutense de Madrid (UCM), Madrid, Spain.
Brenda ChinoCenter of Cognitive and Computational Neuroscience, Universidad Complutense de Madrid (UCM), Madrid, Spain.
Lucia H OrozcoCenter of Cognitive and Computational Neuroscience, Universidad Complutense de Madrid (UCM), Madrid, Spain.
Elisabeth B MarshDepartment of Neurology, The Johns Hopkins School of Medicine, Baltimore, MD, United States.
Pedro GilInstituto de investigación Sanitaria San Carlos (IdISSC), Madrid, Spain.
Fernando MaestuCenter of Cognitive and Computational Neuroscience, Universidad Complutense de Madrid (UCM), Madrid, Spain.
Universidad Complutense de Madrid · ESInstituto de Investigación Sanitaria del Hospital Clínico San Carlos · ESJohns Hopkins University · USUniversitat Autònoma de Barcelona · ES

Funding

Digital Biomarkers for Vascular Cognitive Decline in Patients with Minor StrokeRF1AG079324 · NIA · JOHNS HOPKINS UNIVERSITY · PI MARSH, ELISABETH BREESE, MOSHER, JOHN COMPTON · 2022 to 2025
$3.8M
Digital biomarker for a low cost ambulatory test for early detection of Alzheimer's diseaseRF1AG074204 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI FUNKE, MICHAEL, MOSHER, JOHN COMPTON · 2021 to 2021
$2.1M
Digital biomarker for a low cost ambulatory test for early detection of Alzheimer's diseaseR01AG074204 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI FUNKE, MICHAEL, MOSHER, JOHN COMPTON · 2024 to 2025
$1.3M
Mindfulness Matters: TheImpact of Mindfulness Based Stress Reduction on Post-Stroke CognitionR21AG068802 · NIA · JOHNS HOPKINS UNIVERSITY · PI MARSH, ELISABETH BREESE · 2020 to 2020
$460k
NIA NIH HHS R01 AG074204NIA NIH HHS R21 AG068802NIA NIH HHS RF1 AG074204NIA NIH HHS RF1 AG079324
6 · The paper itself

Abstract

Cerebrovascular disease is responsible for up to 20% of cases of dementia worldwide, but also it is a major comorbid contributor to the progression of other neurodegenerative diseases, like Alzheimer's disease. White matter hyperintensities (WMH) are the most prevalent imaging marker in cerebrovascular disease. The presence and progression of WMH in the brain have been associated with general cognitive impairment and the risk to develop all types of dementia. The aim of this piece of work is the assessment of brain functional differences in an MCI population based on the WMH volume. One-hundred and twenty-nine individuals with mild cognitive impairment (MCI) underwent a neuropsychological evaluation, MRI assessment (T1 and Flair), and MEG recordings (5 min of eyes closed resting state). Those participants were further classified into vascular MCI (vMCI;

Indexed as

cerebrovascular disease (CVD)magnetoencephalography (MEG)mild cognitive impairmentpower spectra analysissmall vessel cerebral diseasewhite matter hyperintensites

Identifiers

PMID36875239
PMCPMC9977191
OpenAlexW4320921010

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.