Evidence map›Paper›PMID 36875196›Full record

ArticleThe Malaysian journal of medical sciences : MJMS2023

The Antioxidant Activity and Induction of Apoptotic Cell Death by

Mohd Nur Nasyriq Anuar, Muhammad Ibrahim, Nor Hafizah Zakaria, Solachuddin Jauhari Arief Ichwan, Muhammad Lokman Md Isa, Nur Aizura Mat Alewi, Abdullah Hagar, Fadzilah Adibah Abdul Majid

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Malaysian journal of medical sciences : MJMS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Reflecting on Progress of theThe Malaysian journal of medical sciences : MJMS · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mohd Nur Nasyriq AnuarDepartment of Nutrition Sciences, Kulliyyah of Allied Health Sciences, International Islamic University Malaysia, Pahang, Malaysia.
Muhammad IbrahimDepartment of Nutrition Sciences, Kulliyyah of Allied Health Sciences, International Islamic University Malaysia, Pahang, Malaysia.
Nor Hafizah ZakariaInstitute of Marine Biotechnology, Universiti Malaysia Terengganu, Kuala Nerus, Terengganu, Malaysia.
Solachuddin Jauhari Arief IchwanDentistry Programme, PAPRSB Institute of Health Sciences, Universiti Brunei Darussalam, Gadong, Brunei Darussalam.
Muhammad Lokman Md IsaDepartment of Basic Medical Sciences for Nursing, Kulliyyah of Nursing, International Islamic University Malaysia, Pahang, Malaysia.
Nur Aizura Mat AlewiDepartment of Nutrition Sciences, Kulliyyah of Allied Health Sciences, International Islamic University Malaysia, Pahang, Malaysia.
Abdullah HagarDepartment of Nutrition Sciences, Kulliyyah of Allied Health Sciences, International Islamic University Malaysia, Pahang, Malaysia.
Fadzilah Adibah Abdul MajidInstitute of Marine Biotechnology, Universiti Malaysia Terengganu, Kuala Nerus, Terengganu, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Head and neck cancer patients usually need nutritional support due to difficulties in swallowing and chewing. Therefore, this study aimed to formulate Methods: The antioxidant properties were analysed using 2,2'-diphenyl-1 picrylhydrazyl (DPPH), ferric reducing antioxidant potential (FRAP) and 2,2'-azinodi 3-ethylbenthiazolinesulfonate (ABTS) assays. Cytotoxicity was assayed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) test and the induction of apoptosis was observed via caspase-3/7 activity assay. The identification of phenolic compounds was done via ultra-high-performance-liquid chromatography coupled to mass spectrometer (UHPLC-MS/MS). Results: The antioxidant analysis exhibited: the half inhibitory concentration (IC Conclusion: The study evidenced that the antioxidant activity of MTJ could influence the induction of apoptosis in ORL115 and ORL188 in future investigations and verifications.

Indexed as

antioxidantapoptosishead and neck squamous cell carcinomaMusa paradisiacastingless bee

Identifiers

PMID36875196
PMCPMC9984108

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.