Evidence map›Paper›PMID 36875136›Full record

ReviewFrontiers in immunology2023

Effects of hepatitis B virus infection and strategies for preventing mother-to-child transmission on maternal and fetal T-cell immunity.

Huihui Lu, Weihua Cao, Luxue Zhang, Liu Yang, Xiaoyue Bi, Yanjie Lin, Wen Deng, Tingting Jiang, Fangfang Sun, Zhan Zeng and 14 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Comprehensive Interventions in HBV Care: Nursing-Sensitive Approach.Gynecologic and obstetric investigation · 2025
    Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 4 institutions in 1 country.

Huihui LuDepartment of Hepatology Division 2, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Weihua CaoDepartment of Hepatology Division 2, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Luxue ZhangInfectious Disease Department, Xuanwu Hospital, Capital Medical University, Beijing, China.
Liu YangDepartment of Hepatology Division 2, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Xiaoyue BiDepartment of Hepatology Division 2, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Yanjie LinDepartment of Hepatology Division 2, Peking University Ditan Teaching Hospital, Beijing, China.
Wen DengDepartment of Hepatology Division 2, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Tingting JiangDepartment of Hepatology Division 2, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Fangfang SunDepartment of Hepatology Division 2, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Zhan ZengDepartment of Hepatology Division 2, Peking University Ditan Teaching Hospital, Beijing, China.
Yao LuDepartment of Hepatology Division 2, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Lu ZhangDepartment of Hepatology Division 2, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Ruyu LiuDepartment of Hepatology Division 2, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Yuanjiao GaoDepartment of Hepatology Division 2, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Shuling WuDepartment of Hepatology Division 2, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Hongxiao HaoDepartment of Hepatology Division 2, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Xiaoxue ChenDepartment of Hepatology Division 2, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Leiping HuDepartment of Hepatology Division 2, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Mengjiao XuDepartment of Hepatology Division 2, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Qiqiu XiongDepartment of General Surgery, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Jianping DongDepartment of Infectious Disease, Haidian Hospital, Beijing Haidian Section of Peking University Third Hospital, Beijing, China.
Rui SongDepartment of Infectious Disease, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Minghui LiDepartment of Hepatology Division 2, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Yao XieDepartment of Hepatology Division 2, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Capital Medical University · CNBeijing Ditan Hospital · CNPeking University · CNBeijing Haidian Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the most common routes of chronic hepatitis B virus (HBV) infection is mother-to-child transmission (MTCT). Approximately 6.4 million children under the age of five have chronic HBV infections worldwide. HBV DNA high level, HBeAg positivity, placental barrier failure, and immaturity of the fetal immune are the possible causes of chronic HBV infection. The passive-active immune program for children, which consists of the hepatitis B vaccine and hepatitis B immunoglobulin, and antiviral therapy for pregnant women who have a high HBV DNA load (greater than 2 × 10

Indexed as

Hepatitis BHepatitis B, ChronicDNA, ViralFemaleHepatitis B e AntigensHepatitis B virusHumansInfantInfectious Disease Transmission, VerticalPlacentaPregnancyT-LymphocytesDNA, ViralHepatitis B e Antigenseffectshepatitis B virusimmunological characteristicsmother-to-child transmissionpregnancyT-cell immunity

Identifiers

PMID36875136
PMCPMC9978148
OpenAlexW4321094675

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.