Evidence map›Paper›PMID 36875051›Full record

ArticleBioactive materials2023

Detailing the influence of PEO-coated biodegradable Mg-based implants on the lacuno-canalicular network in sheep bone: A pilot study.

Jonathan Espiritu, Sandra Sefa, Hanna Ćwieka, Imke Greving, Silja Flenner, Regine Willumeit-Römer, Jan-Marten Seitz, Berit Zeller-Plumhoff

Abstract read
In one paragraph

Article in Bioactive materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jonathan EspirituSyntellix AG, Hannover, Germany.
Sandra SefaInstitute of Metallic Biomaterials, Helmholtz-Zentrum Hereon, Geesthacht, Germany.
Hanna ĆwiekaInstitute of Metallic Biomaterials, Helmholtz-Zentrum Hereon, Geesthacht, Germany.
Imke GrevingInstitute of Materials Physics, Helmholtz-Zentrum Hereon, Geesthacht, Germany.
Silja FlennerInstitute of Materials Physics, Helmholtz-Zentrum Hereon, Geesthacht, Germany.
Regine Willumeit-RömerInstitute of Metallic Biomaterials, Helmholtz-Zentrum Hereon, Geesthacht, Germany.
Jan-Marten SeitzSyntellix AG, Hannover, Germany.
Berit Zeller-PlumhoffInstitute of Metallic Biomaterials, Helmholtz-Zentrum Hereon, Geesthacht, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An increasing prevalence of bone-related injuries and aging geriatric populations continue to drive the orthopaedic implant market. A hierarchical analysis of bone remodelling after material implantation is necessary to better understand the relationship between implant and bone. Osteocytes, which are housed and communicate through the lacuno-canalicular network (LCN), are integral to bone health and remodelling processes. Therefore, it is essential to examine the framework of the LCN in response to implant materials or surface treatments. Biodegradable materials offer an alternative solution to permanent implants, which may require revision or removal surgeries. Magnesium alloys have resurfaced as promising materials due to their bone-like properties and safe degradation

Indexed as

Biodegradable implantsBoneLacuno-canalicular networkMagnesiumNanotomography

Identifiers

PMID36875051
PMCPMC9975618

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.