ArticleNetwork neuroscience (Cambridge, Mass.)2022
A natural cortical axis connecting the outside and inside of the human brain.
Article in Network neuroscience (Cambridge, Mass.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 28 citations in OpenAlex.
- Human cortical dynamics reflect graded contributions of local geometry and network topography.Nature communications · 2025Article
- Humans have a longer period of cortical maturation across depth and hierarchy than macaques.PLoS biology · 2025Article
- The architecture of the human default mode network explored through cytoarchitecture, wiring and signal flow.Nature neuroscience · 2025Article
- Myelination across cortical hierarchies and depths in humans and macaques.bioRxiv : the preprint server for biology · 2025Article
- Review
- The alterations of repetitive transcranial magnetic stimulation on the energy landscape of resting-state networks differ across the human cortex.Human brain mapping · 2024Article
- Socioeconomic resources in youth are linked to divergent patterns of network integration/segregation across the brain's transmodal axis.PNAS nexus · 2024Article
- A shifting role of thalamocortical connectivity in the emergence of cortical functional organization.Nature neuroscience · 2024Article
- Cortical gene expression architecture links healthy neurodevelopment to the imaging, transcriptomics and genetics of autism and schizophrenia.Nature neuroscience · 2024Article
- Taking time to compose thoughts with prefrontal schemata.Experimental brain research · 2024Article
- Mapping and comparing fMRI connectivity networks across species.Communications biology · 2023Review
- Socioeconomic resources in youth are linked to divergent patterns of network integration and segregation across the brain's transmodal axis.bioRxiv : the preprint server for biology · 2023Article
- Correspondence of functional connectivity gradients across human isocortex, cerebellum, and hippocampus.Communications biology · 2023Article
- Intrinsic activity development unfolds along a sensorimotor-association cortical axis in youth.Nature neuroscience · 2023Article
- Hierarchical functional system development supports executive function.Trends in cognitive sciences · 2023Review
- neuromaps: structural and functional interpretation of brain maps.Nature methods · 2022Article
- Editorial: Focus feature on consciousness and cognition.Network neuroscience (Cambridge, Mass.) · 2022Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
What structural and connectivity features of the human brain help to explain the extraordinary human cognitive abilities? We recently proposed a set of relevant connectomic fundamentals, some of which arise from the size scaling of the human brain relative to other primate brains, while others of these fundamentals may be uniquely human. In particular, we suggested that the remarkable increase of the size of the human brain due to its prolonged prenatal development has brought with it an increased sparsification, hierarchical modularization, as well as increased depth and cytoarchitectonic differentiation of brain networks. These characteristic features are complemented by a shift of projection origins to the upper layers of many cortical areas as well as the significantly prolonged postnatal development and plasticity of the upper cortical layers. Another fundamental aspect of cortical organization that has emerged in recent research is the alignment of diverse features of evolution, development, cytoarchitectonics, function, and plasticity along a principal, natural cortical axis from sensory ("outside") to association ("inside") areas. Here we highlight how this natural axis is integrated in the characteristic organization of the human brain. In particular, the human brain displays a developmental expansion of outside areas and a stretching of the natural axis such that outside areas are more widely separated from each other and from inside areas than in other species. We outline some functional implications of this characteristic arrangement.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.