Evidence map›Paper›PMID 36874540›Full record

ArticleThe Canadian veterinary journal = La revue veterinaire canadienne2023

Effects of naturally acquired gastrointestinal nematode infection on bovine viral diarrhea virus vaccine-directed antibody response in western Canadian feedlot cattle.

Eranga L De Seram, John R Campbell, Colleen M Pollock, Samantha Ekanayake, Karen Gesy, John S Gilleard, Gregory B Penner, Fabienne D Uehlinger

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Bovine viral diarrhea virus and virus-neutralizing antibody titers in beef calves at or near fall weaning.The Canadian veterinary journal = La revue veterinaire canadienne · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Eranga L De SeramDepartment of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4 (Seram, Campbell, Ekanayake, Gesy, Uehlinger); Merck Animal Health Canada, Intervet Canada Corp., 16750 Trans Canada Hwy, Kirkland, Quebec H9H 4M7 (Pollock); Faculty of Veterinary Medicine, University of Calgary, 3280 Hospital Drive NW, Calgary, Alberta T2N 4Z6 (Gilleard); Department of Animal and Poultry Science, Agriculture building, University of Saskatchewan, 51 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Penner).
John R CampbellDepartment of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4 (Seram, Campbell, Ekanayake, Gesy, Uehlinger); Merck Animal Health Canada, Intervet Canada Corp., 16750 Trans Canada Hwy, Kirkland, Quebec H9H 4M7 (Pollock); Faculty of Veterinary Medicine, University of Calgary, 3280 Hospital Drive NW, Calgary, Alberta T2N 4Z6 (Gilleard); Department of Animal and Poultry Science, Agriculture building, University of Saskatchewan, 51 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Penner).
Colleen M PollockDepartment of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4 (Seram, Campbell, Ekanayake, Gesy, Uehlinger); Merck Animal Health Canada, Intervet Canada Corp., 16750 Trans Canada Hwy, Kirkland, Quebec H9H 4M7 (Pollock); Faculty of Veterinary Medicine, University of Calgary, 3280 Hospital Drive NW, Calgary, Alberta T2N 4Z6 (Gilleard); Department of Animal and Poultry Science, Agriculture building, University of Saskatchewan, 51 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Penner).
Samantha EkanayakeDepartment of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4 (Seram, Campbell, Ekanayake, Gesy, Uehlinger); Merck Animal Health Canada, Intervet Canada Corp., 16750 Trans Canada Hwy, Kirkland, Quebec H9H 4M7 (Pollock); Faculty of Veterinary Medicine, University of Calgary, 3280 Hospital Drive NW, Calgary, Alberta T2N 4Z6 (Gilleard); Department of Animal and Poultry Science, Agriculture building, University of Saskatchewan, 51 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Penner).
Karen GesyDepartment of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4 (Seram, Campbell, Ekanayake, Gesy, Uehlinger); Merck Animal Health Canada, Intervet Canada Corp., 16750 Trans Canada Hwy, Kirkland, Quebec H9H 4M7 (Pollock); Faculty of Veterinary Medicine, University of Calgary, 3280 Hospital Drive NW, Calgary, Alberta T2N 4Z6 (Gilleard); Department of Animal and Poultry Science, Agriculture building, University of Saskatchewan, 51 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Penner).
John S GilleardDepartment of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4 (Seram, Campbell, Ekanayake, Gesy, Uehlinger); Merck Animal Health Canada, Intervet Canada Corp., 16750 Trans Canada Hwy, Kirkland, Quebec H9H 4M7 (Pollock); Faculty of Veterinary Medicine, University of Calgary, 3280 Hospital Drive NW, Calgary, Alberta T2N 4Z6 (Gilleard); Department of Animal and Poultry Science, Agriculture building, University of Saskatchewan, 51 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Penner).
Gregory B PennerDepartment of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4 (Seram, Campbell, Ekanayake, Gesy, Uehlinger); Merck Animal Health Canada, Intervet Canada Corp., 16750 Trans Canada Hwy, Kirkland, Quebec H9H 4M7 (Pollock); Faculty of Veterinary Medicine, University of Calgary, 3280 Hospital Drive NW, Calgary, Alberta T2N 4Z6 (Gilleard); Department of Animal and Poultry Science, Agriculture building, University of Saskatchewan, 51 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Penner).
Fabienne D UehlingerDepartment of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4 (Seram, Campbell, Ekanayake, Gesy, Uehlinger); Merck Animal Health Canada, Intervet Canada Corp., 16750 Trans Canada Hwy, Kirkland, Quebec H9H 4M7 (Pollock); Faculty of Veterinary Medicine, University of Calgary, 3280 Hospital Drive NW, Calgary, Alberta T2N 4Z6 (Gilleard); Department of Animal and Poultry Science, Agriculture building, University of Saskatchewan, 51 Campus Drive, Saskatoon, Saskatchewan S7N 5A8 (Penner).
University of Saskatchewan · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To determine how gastrointestinal nematode (GIN) infection, reflected by fecal egg counts and Animals: Cross-sectional study with 240 steer calves derived from an auction market. Procedure: At feedlot arrival, calves were given a commercial vaccine containing modified live BVDV-1. Serum neutralization antibody titers against BVDV-1 antigens were determined in individual blood samples collected pre-vaccination and 21 d after vaccination. A modified Wisconsin sugar floatation method was used to obtain individual calf GIN egg counts in fecal samples on arrival. Antibody titers against Results: Fecal egg counts and Conclusions: The relatively low GIN burdens, reflected by the overall low fecal egg counts in these fall-weaned feedlot calves, did not have measurable adverse effects on the humoral immune response to BVDV-1 vaccine antigens. Clinical relevance: An adequate response to vaccination is important for cattle welfare and productivity. Conditions that negatively affect this response may vary regionally, such as GIN infection. Understanding this is essential. Although subclinical intestinal parasitism did not noticeably affect the antibody response in these steers, higher GIN burdens and actual immune protection from clinical disease remain to be investigated.

Indexed as

Cattle DiseasesCommunicable DiseasesGastrointestinal DiseasesNematodaNematode InfectionsVaccinesAnimalsAntibodies, ViralAntibody FormationCanadaCattleCross-Sectional StudiesDiarrheaAntibodies, ViralVaccines

Identifiers

PMID36874540
PMCPMC9979757
OpenAlexW4323294800

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.