Evidence map›Paper›PMID 36874504›Full record

ArticleBiomedical optics express2023

Surgical microscope integrated MHz SS-OCT with live volumetric visualization.

Anja Britten, Philipp Matten, Jakob Weiss, Michael Niederleithner, Hessam Roodaki, Benjamin Sorg, Nancy Hecker-Denschlag, Wolfgang Drexler, Rainer A Leitgeb, Tilman Schmoll

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
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  6. Real-time Deformation-aware Control for Autonomous Robotic Subretinal Injection under iOCT Guidance.IEEE International Conference on Robotics and Automation : ICRA : [proceedings]. IEEE International Conference on Robotics and Automation · 2025
    Article
  7. Article
  8. Review
  9. New Directions for Ophthalmic OCT - Handhelds, Surgery, and Robotics.Translational vision science & technology · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Exploring the Needle Tip Interaction Force with Retinal Tissue Deformation in Vitreoretinal Surgery.IEEE International Conference on Robotics and Automation : ICRA : [proceedings]. IEEE International Conference on Robotics and Automation · 2024
    Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Anja BrittenCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringer Guertel 18-20, 4 L, 1090 Vienna, Austria.ORCID https://orcid.org/0000-0002-6527-7081
Philipp MattenCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringer Guertel 18-20, 4 L, 1090 Vienna, Austria.ORCID https://orcid.org/0000-0001-6874-8435
Jakob WeissChair for Computer Aided Medical Procedures, Technical University of Munich, Boltzmannstrasse 385748 Munich, Germany.
Michael NiederleithnerCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringer Guertel 18-20, 4 L, 1090 Vienna, Austria.
Hessam RoodakiCarl Zeiss Meditec AG, Kistlerhofstrasse 75, 81379 Munich, Germany.
Benjamin SorgCarl Zeiss Meditec AG, Rudolf-Eber-Strasse 11, 73447 Oberkochen, Germany.
Nancy Hecker-DenschlagCarl Zeiss Meditec AG, Rudolf-Eber-Strasse 11, 73447 Oberkochen, Germany.
Wolfgang DrexlerCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringer Guertel 18-20, 4 L, 1090 Vienna, Austria.
Rainer A LeitgebCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringer Guertel 18-20, 4 L, 1090 Vienna, Austria.
Tilman SchmollCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringer Guertel 18-20, 4 L, 1090 Vienna, Austria.
Medical University of Vienna · ATCarl Zeiss (United States) · USTechnical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intraoperative optical coherence tomography is still not overly pervasive in routine ophthalmic surgery, despite evident clinical benefits. That is because today's spectral-domain optical coherence tomography systems lack flexibility, acquisition speed, and imaging depth. We present to the best of our knowledge the most flexible swept-source optical coherence tomography (SS-OCT) engine coupled to an ophthalmic surgical microscope that operates at MHz A-scan rates. We use a MEMS tunable VCSEL to implement application-specific imaging modes, enabling diagnostic and documentary capture scans, live B-scan visualizations, and real-time 4D-OCT renderings. The technical design and implementation of the SS-OCT engine, as well as the reconstruction and rendering platform, are presented. All imaging modes are evaluated in surgical mock maneuvers using ex vivo bovine and porcine eye models. The applicability and limitations of MHz SS-OCT as a visualization tool for ophthalmic surgery are discussed.

Identifiers

PMID36874504
PMCPMC9979659
OpenAlexW4313989387

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.