Evidence map›Paper›PMID 36874495›Full record

ReviewBiomedical optics express2023

Optical ptychography for biomedical imaging: recent progress and future directions [Invited].

Tianbo Wang, Shaowei Jiang, Pengming Song, Ruihai Wang, Liming Yang, Terrance Zhang, Guoan Zheng

Abstract readReview
In one paragraph

Review in Biomedical optics express, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Multiscale aperture synthesis imager.Nature communications · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Quantitative imaging of individual bacterial cells:Journal of biomedical optics · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Ptychography at all wavelengths.Nature reviews. Methods primers · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. On the use of deep learning for phase recovery.Light, science & applications · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tianbo WangDepartment of Biomedical Engineering, University of Connecticut, Storrs, CT 06269, USA.
Shaowei JiangDepartment of Biomedical Engineering, University of Connecticut, Storrs, CT 06269, USA.
Pengming SongDepartment of Biomedical Engineering, University of Connecticut, Storrs, CT 06269, USA.
Ruihai WangDepartment of Biomedical Engineering, University of Connecticut, Storrs, CT 06269, USA.
Liming YangDepartment of Biomedical Engineering, University of Connecticut, Storrs, CT 06269, USA.
Terrance ZhangDepartment of Biomedical Engineering, University of Connecticut, Storrs, CT 06269, USA.
Guoan ZhengDepartment of Biomedical Engineering, University of Connecticut, Storrs, CT 06269, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ptychography is an enabling microscopy technique for both fundamental and applied sciences. In the past decade, it has become an indispensable imaging tool in most X-ray synchrotrons and national laboratories worldwide. However, ptychography's limited resolution and throughput in the visible light regime have prevented its wide adoption in biomedical research. Recent developments in this technique have resolved these issues and offer turnkey solutions for high-throughput optical imaging with minimum hardware modifications. The demonstrated imaging throughput is now greater than that of a high-end whole slide scanner. In this review, we discuss the basic principle of ptychography and summarize the main milestones of its development. Different ptychographic implementations are categorized into four groups based on their lensless/lens-based configurations and coded-illumination/coded-detection operations. We also highlight the related biomedical applications, including digital pathology, drug screening, urinalysis, blood analysis, cytometric analysis, rare cell screening, cell culture monitoring, cell and tissue imaging in 2D and 3D, polarimetric analysis, among others. Ptychography for high-throughput optical imaging, currently in its early stages, will continue to improve in performance and expand in its applications. We conclude this review article by pointing out several directions for its future development.

Identifiers

PMID36874495
PMCPMC9979669

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.