Evidence map›Paper›PMID 36874474›Full record

ArticleJournal of molecular liquids2023

Tenofovir antiviral drug solubility enhancement with β-cyclodextrin inclusion complex and

Sonaimuthu Mohandoss, Kuppu Sakthi Velu, Thambusamy Stalin, Naushad Ahmad, Suliman Yousef Alomar, Yong Rok Lee

Open access · greenAbstract read
In one paragraph

Article in Journal of molecular liquids, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  3. Crosslinked PVA-ACS omega · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Sonaimuthu MohandossSchool of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Kuppu Sakthi VeluDepartment of Industrial Chemistry, Alagappa University, Karikudi 630003, Tamilnadu, India.
Thambusamy StalinDepartment of Industrial Chemistry, Alagappa University, Karikudi 630003, Tamilnadu, India.
Naushad AhmadDepartment of Chemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Suliman Yousef AlomarDoping Research Chair, Zoology Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Yong Rok LeeSchool of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Alagappa University · INKing Saud University · SAYeungnam University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tenofovir (TFR) is an antiviral drug commonly used to fight against viral diseases infection due to its good potency and high genetic barrier to drug resistance. In physiological conditions, TFR is less water soluble, more unstable, and less permeable, limiting its effective therapeutic applications. In addition to their use in treating the Coronavirus disease 2019 (COVID-19), cyclodextrins (CDs) are also being used as a molecule to develop therapies for other diseases due to its enhance solubility and stability. This study is designed to synthesize and characterization of β-CD:TFR inclusion complex and its interaction against SARS-CoV-2 (M

Indexed as

Inclusion complexIn silicoSARS-CoV-2SolubilityTenofovirβ-cyclodextrin

Identifiers

PMID36874474
PMCPMC9968670
OpenAlexW4322504955

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.