Evidence map›Paper›PMID 36874248›Full record

ArticleCardiovascular therapeutics2023

Pharmacological Activation of Rev-erb

Runmei Zou, Shuo Wang, Hong Cai, Yuwen Wang, Cheng Wang

Open access · goldAbstract read
In one paragraph

Article in Cardiovascular therapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Research Progress of BMAL1 in Heart Failure.Journal of the American Heart Association · 2025
    Review
  4. Doxorubicin-Induced Cardiotoxicity: A Comprehensive Update.Journal of cardiovascular development and disease · 2025
    Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Runmei ZouDepartment of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University, Changsha, China.ORCID https://orcid.org/0000-0002-3840-855X
Shuo WangDepartment of Neonatology, Xiangya Hospital, Central South University, Changsha, China.ORCID https://orcid.org/0000-0001-5095-1435
Hong CaiDepartment of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University, Changsha, China.ORCID https://orcid.org/0000-0002-6398-0697
Yuwen WangDepartment of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University, Changsha, China.ORCID https://orcid.org/0000-0002-1627-8918
Cheng WangDepartment of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University, Changsha, China.ORCID https://orcid.org/0000-0002-7120-0654
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Doxorubicin-induced cardiotoxicity has been closely concerned in clinical practice. Rev-erb Methods: H9c2 cells were treated with 1.5 Results: SR9009 alleviated doxorubicin-induced cell apoptosis, morphological disorder, mitochondrial dysfunction, and oxidative stress in H9c2 cells and C57BL/6 mice. Meanwhile, PGC-1 Conclusion: Pharmacological activation of Rev-erb

Indexed as

CardiotoxicitySignal TransductionAnimalsDoxorubicinMiceMice, Inbred C57BLPyrrolidinesRNA, Small InterferingThiophenesDoxorubicinPyrrolidinesRNA, Small InterferingSR9009Thiophenes

Identifiers

PMID36874248
PMCPMC9977526
OpenAlexW4321486525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.