Evidence map›Paper›PMID 36874245›Full record

ArticleMolecular therapy. Methods & clinical development2023

Efficacy of oligodendrocyte precursor cells as delivery vehicles for single-chain variable fragment to misfolded SOD1 in ALS rat model.

Sumio Minamiyama, Madoka Sakai, Yuko Yamaguchi, Makiko Kusui, Hideki Wada, Ryota Hikiami, Yoshitaka Tamaki, Megumi Asada-Utsugi, Akemi Shodai, Akiko Makino and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular therapy. Methods & clinical development, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. A novel antibody to treat SOD1-related amyotrophic lateral sclerosis.Molecular therapy. Methods & clinical development · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Sumio MinamiyamaDepartment of Neurology, Shiga University of Medical Science, Otsu, Shiga 5202192, Japan.
Madoka SakaiLaboratory of RNA Viruses, Department of Virus Research, Institute for Frontier Life and Medical Sciences (InFRONT), Kyoto University, Kyoto 6068507, Japan.
Yuko YamaguchiDepartment of Neurology, Kyoto University Graduate School of Medicine, Kyoto 6068507, Japan.
Makiko KusuiDepartment of Neurology, Shiga University of Medical Science, Otsu, Shiga 5202192, Japan.
Hideki WadaDepartment of Neurology, Shiga University of Medical Science, Otsu, Shiga 5202192, Japan.
Ryota HikiamiDepartment of Neurology, Shiga University of Medical Science, Otsu, Shiga 5202192, Japan.
Yoshitaka TamakiDepartment of Neurology, Shiga University of Medical Science, Otsu, Shiga 5202192, Japan.
Megumi Asada-UtsugiDepartment of Neurology, Shiga University of Medical Science, Otsu, Shiga 5202192, Japan.
Akemi ShodaiDepartment of Neurology, Shiga University of Medical Science, Otsu, Shiga 5202192, Japan.
Akiko MakinoLaboratory of RNA Viruses, Department of Virus Research, Institute for Frontier Life and Medical Sciences (InFRONT), Kyoto University, Kyoto 6068507, Japan.
Noriko FujiwaraDepartment of Biochemistry, School of Medicine, Hyogo Medical University, Nishinomiya, Hyogo 6638501, Japan.
Takashi AyakiDepartment of Neurology, Kyoto University Graduate School of Medicine, Kyoto 6068507, Japan.
Takakuni MakiDepartment of Neurology, Kyoto University Graduate School of Medicine, Kyoto 6068507, Japan.
Hitoshi WaritaDepartment of Neurology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 9808574, Japan.
Masashi AokiDepartment of Neurology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 9808574, Japan.
Keizo TomonagaLaboratory of RNA Viruses, Department of Virus Research, Institute for Frontier Life and Medical Sciences (InFRONT), Kyoto University, Kyoto 6068507, Japan.
Ryosuke TakahashiDepartment of Neurology, Kyoto University Graduate School of Medicine, Kyoto 6068507, Japan.
Makoto UrushitaniDepartment of Neurology, Shiga University of Medical Science, Otsu, Shiga 5202192, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

amyotrophic lateral sclerosis (ALS)oligodendrocyte precursor cellssingle-chain variable fragments (scFv)superoxide dismutase 1 (SOD1)transplantationviral vector

Identifiers

PMID36874245
PMCPMC9974989

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.