Evidence map›Paper›PMID 36874163›Full record

ReviewComputational and structural biotechnology journal2023

Bioinformatics approaches for unveiling virus-host interactions.

Hitoshi Iuchi, Junna Kawasaki, Kento Kubo, Tsukasa Fukunaga, Koki Hokao, Gentaro Yokoyama, Akiko Ichinose, Kanta Suga, Michiaki Hamada

Abstract readReview
In one paragraph

Review in Computational and structural biotechnology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Computational Analysis of Virus-Host Interactomes.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  10. Article
  11. Review
  12. Article
  13. Systems Biology Approaches to Understanding COVID-19 Spread in the Population.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  14. Hepatitis B Virus and microRNAs: A Bioinformatics Approach.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hitoshi IuchiWaseda Research Institute for Science and Engineering, Waseda University, Tokyo 169-8555, Japan.
Junna KawasakiFaculty of Science and Engineering, Waseda University, Okubo Shinjuku-ku, Tokyo 169-8555, Japan.
Kento KuboComputational Bio Big-Data Open Innovation Laboratory (CBBD-OIL), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo 169-8555, Japan.
Tsukasa FukunagaWaseda Institute for Advanced Study, Waseda University, Nishi Waseda, Shinjuku-ku, Tokyo 169-0051, Japan.
Koki HokaoSchool of Advanced Science and Engineering, Waseda University, Okubo Shinjuku-ku, Tokyo 169-8555, Japan.
Gentaro YokoyamaComputational Bio Big-Data Open Innovation Laboratory (CBBD-OIL), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo 169-8555, Japan.
Akiko IchinoseWaseda Research Institute for Science and Engineering, Waseda University, Tokyo 169-8555, Japan.
Kanta SugaSchool of Advanced Science and Engineering, Waseda University, Okubo Shinjuku-ku, Tokyo 169-8555, Japan.
Michiaki HamadaWaseda Research Institute for Science and Engineering, Waseda University, Tokyo 169-8555, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus disease-2019 (COVID-19) pandemic has elucidated major limitations in the capacity of medical and research institutions to appropriately manage emerging infectious diseases. We can improve our understanding of infectious diseases by unveiling virus-host interactions through host range prediction and protein-protein interaction prediction. Although many algorithms have been developed to predict virus-host interactions, numerous issues remain to be solved, and the entire network remains veiled. In this review, we comprehensively surveyed algorithms used to predict virus-host interactions. We also discuss the current challenges, such as dataset biases toward highly pathogenic viruses, and the potential solutions. The complete prediction of virus-host interactions remains difficult; however, bioinformatics can contribute to progress in research on infectious diseases and human health.

Indexed as

Host range predictionProtein–protein interaction predictionVirus–host interaction

Identifiers

PMID36874163
PMCPMC9969756

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.