Evidence map›Paper›PMID 36874014›Full record

ArticleFrontiers in pharmacology2023

Dietary methionine restriction alleviates oxidative stress and inflammatory responses in lipopolysaccharide-challenged broilers at early age.

Xiyuan Pang, Zhiqiang Miao, Yuanyang Dong, Huiyu Cheng, Xiangqi Xin, Yuan Wu, Miaomiao Han, Yuan Su, Jianmin Yuan, Yuxin Shao and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Xiyuan PangCollege of Animal Sciences, Shanxi Agricultural University, Taigu, China.
Zhiqiang MiaoCollege of Animal Sciences, Shanxi Agricultural University, Taigu, China.
Yuanyang DongCollege of Animal Sciences, Shanxi Agricultural University, Taigu, China.
Huiyu ChengCollege of Animal Sciences, Shanxi Agricultural University, Taigu, China.
Xiangqi XinCollege of Animal Sciences, Shanxi Agricultural University, Taigu, China.
Yuan WuCollege of Animal Sciences, Shanxi Agricultural University, Taigu, China.
Miaomiao HanCollege of Animal Sciences, Shanxi Agricultural University, Taigu, China.
Yuan SuCollege of Animal Sciences, Shanxi Agricultural University, Taigu, China.
Jianmin YuanCollege of Animal Sciences and Technology, China Agricultural University, Beijing, China.
Yuxin ShaoInstitute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, Beijing, China.
Lei YanNew Hope Liuhe Co.,Ltd., Beijing, China.
Jianhui LiCollege of Animal Sciences, Shanxi Agricultural University, Taigu, China.
Shanxi Agricultural University · CNBeijing Academy of Agricultural and Forestry Sciences · CNChina Agricultural University · CNNew Hope Liuhe (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we investigated the effect of dietary methionine restriction (MR) on the antioxidant function and inflammatory responses in lipopolysaccharide (LPS)-challenged broilers reared at high stocking density. A total of 504 one-day-old male Arbor Acre broiler chickens were randomly divided into four treatments: 1) CON group, broilers fed a basal diet; 2) LPS group, LPS-challenged broilers fed a basal diet; 3) MR1 group, LPS-challenged broilers fed a methionine-restricted diet (0.3% methionine); and 4) MR2 group, LPS-challenged broilers fed a methionine-restricted diet (0.4% methionine). LPS-challenged broilers were intraperitoneally injected with 1 mg/kg body weight (BW) of LPS at 17, 19, and 21 days of age, whereas the CON group was injected with sterile saline. The results showed that: LPS significantly increased the liver histopathological score (

Indexed as

antioxidant capacitybroilersinflammationlipopolysaccharideliver healthmethionine restriction

Identifiers

PMID36874014
PMCPMC9975741
OpenAlexW4320917687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.