Evidence map›Paper›PMID 36873908›Full record

ArticleIn silico pharmacology2023

In-vivo and in-silico studies revealed the molecular mechanisms of

Deusdedit Tusubira, Jonasi Munezero, Peter Chinedu Agu, Clement Olusoji Ajayi, Joseph Oloro, Nathiim Namale, Frank Ssedyabane, Caroline Kiwanuka Nakiguli, Abayomi E Adegboyega, Patrick Maduabuchi Aja

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In silico pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Journal of experimental pharmacology · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Deusdedit TusubiraBiochemistry Department, Faculty of Medicine, Mbarara University of Science and Technology, P. O. Box 1410, Mbarara, Uganda.ORCID 0000-0002-4698-424X
Jonasi MunezeroBiochemistry Department, Faculty of Medicine, Mbarara University of Science and Technology, P. O. Box 1410, Mbarara, Uganda.
Peter Chinedu AguDepartment of Biochemistry, Faculty of Science, Ebonyi State University, PMB 053, Abakaliki, Nigeria.
Clement Olusoji AjayiPharm-Biotechnology and Traditional Medicine Center, Mbarara, Uganda.
Joseph OloroDepartment of Pharmacology and Therapeutics, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Nathiim NamaleBiochemistry Department, Faculty of Medicine, Mbarara University of Science and Technology, P. O. Box 1410, Mbarara, Uganda.
Frank SsedyabaneMedical Laboratory Science, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Caroline Kiwanuka NakiguliDepartment of Chemistry, Faculty of Science, Mbarara University of Science and Technology, Mbarara, Uganda.
Abayomi E AdegboyegaUniversity of Jos/Jaris Computational Biology Centre, Jos, Nigeria.
Patrick Maduabuchi AjaBiochemistry Department, Faculty of Medicine, Mbarara University of Science and Technology, P. O. Box 1410, Mbarara, Uganda.
Mbarara University of Science and Technology · UGEbonyi State University · NGUniversity of Jos · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Benign Prostatic Hyperplasia (BPH) is a major cause of lower urinary tract infections and erectile dysfunction thus a major contributor to lowering the quality of life among older men. In this study, we investigated the molecular mechanism of Graphical Abstract:

Indexed as

5α-reductaseBPHColocasia esculenta phenolicsLead moleculesMolecular mechanismα1-adrenoceptor

Identifiers

PMID36873908
PMCPMC9978050
OpenAlexW4322740539

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.