ArticleJACC. Asia2023
Midterm Outcomes of Underweight Patients Undergoing Transcatheter Aortic Valve Implantation: Insight From the LAPLACE-TAVR Registry.
Article in JACC. Asia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06503965 (Design and Rationale of the National Multicenter Tunisian Registry of Trans Catheter Aortic Valve Implantation Registry), which is not on this map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Design and Rationale of the National Multicenter Tunisian Registry of Trans Catheter Aortic Valve Implantation Registry
Who cites it
16 citing papers in PubMed, 21 citations in OpenAlex.
- Prognostic utility of serum albumin in underweight patients who underwent isolated surgical aortic valve replacement.General thoracic and cardiovascular surgery · 2026Article
- Impact of Body Mass Index on In-Hospital Outcomes After Transcatheter Aortic Valve Replacement: A Retrospective Cohort Study from Saudi Arabia.Life (Basel, Switzerland) · 2026Article
- BMI Is Unreliable When Studying the Obesity Paradox in TAVR.JACC. Asia · 2026Article
- Reply: BMI is Unreliable When Studying the Obesity Paradox in TAVR.JACC. Asia · 2026Article
- Body Mass Index and Outcomes After Transcatheter Aortic Valve Replacement: Insights From the Transpacific-TAVR Registry.JACC. Asia · 2025Article
- Severity of thinness amplifies mortality risk in patients with transcatheter aortic valve implantation.Interdisciplinary cardiovascular and thoracic surgery · 2025Article
- Impact of in-hospital cardiac rehabilitation on hospital-associated disability after transcatheter aortic valve implantation.Journal of the American Geriatrics Society · 2025Article
- Prognostic impact of being underweight in patients undergoing mitral TEER: The OCEAN-Mitral registry.ESC heart failure · 2025Article
- Epicardial adipose tissue, cardiac damage, and mortality in patients undergoing TAVR for aortic stenosis.The international journal of cardiovascular imaging · 2025Article
- The Triglycerides, total Cholesterol, and Body weight Index associating with frailty and predicting poor outcome after transcatheter aortic valve implantation: insights from LAPLACE-TAVI registry.European heart journal open · 2025Article
- Obesity Paradox in Transcatheter Aortic Valve Replacement.Current cardiology reports · 2024Review
- Article
- Obesity and Transcatheter Aortic Valve Replacement.Journal of cardiovascular development and disease · 2024Review
- Alerting trends in epidemiology for calcific aortic valve disease, 1990-2019: An age-period-cohort analysis for the Global Burden of Disease Study 2019.European heart journal. Quality of care & clinical outcomes · 2023Article
- Article
- Predictive model for severe thrombocytopenia after transfemoral transcatheter aortic valve replacement.Frontiers in cardiovascular medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Obesity is a major risk factor for cardiovascular disease; however, a paradoxical effect of obesity has been reported in patients with heart failure or myocardial infarction. Although several studies have suggested the same obesity paradox in patients undergoing transcatheter aortic valve replacement (TAVR), they included a limited number of underweight patients. Objectives: This study aimed to clarify the effect of being underweight on TAVR outcomes. Methods: We retrospectively analyzed 1,693 consecutive patients undergoing TAVR between 2010 and 2020. The patients were categorized according to body mass index: underweight (<18.5 kg/m Results: Underweight patients were more likely to be women and have severe heart failure symptoms, peripheral artery disease, anemia, hypoalbuminemia, and pulmonary dysfunction. They also had lower ejection fractions, smaller aortic valve areas, and higher surgical risk scores. Device failure, life-threatening bleeding, major vascular complications, and 30-day mortality occurred more frequently in underweight patients. The midterm survival rate of the underweight group was inferior to those of the other 2 groups ( Conclusions: Underweight patients had a worse midterm prognosis, demonstrating the obesity paradox in this TAVR population. (Outcomes of transcatheter aortic valve implantation in Japanese patients with aortic stenosis: multi-center registry; UMIN000031133).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.