Evidence map›Paper›PMID 36873581›Full record

ArticleLeukemia research reports2023

Neuropsychiatric disorders in adults undergoing chimeric antigen receptor T cells therapy for aggressive lymphomas and acute lymphoblastic leukemia.

Josephine Emole, Odunayo Lawal, Oleksandra Lupak, Hemalatha Rangarajan, Itoro Udo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia research reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Josephine EmoleStem Cell Transplantation and Cellular Therapy, Henry Ford Hospital, Detroit, MI, United States.
Odunayo LawalClinical and Translational Science Program, University of Arizona, Tucson, AZ, United States.
Oleksandra LupakHematology/Oncology, Medical University of South Carolina, Charleston, SC, United States.
Hemalatha RangarajanHematology, Oncology & Blood and Marrow Transplant, Nationwide Children's Hospital, Columbus, OH, United States.
Itoro UdoDepartment of Psychiatry, Western University, London, Ontario, Canada.
Henry Ford Hospital · USMedical University of South Carolina · USNationwide Children's Hospital · USUniversity of Arizona · USWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate risk factors for neuropsychiatric disorders (NPD) in recipients of CART therapy. Methods: Patients ≥ 18 years with acute lymphoblastic leukemia (ALL), and aggressive B-cell lymphomas who received CART in 2018 were evaluated. Patients with and without NPD were compared. Results: NPD was diagnosed in 31.2% of patients. Compared to patients without NPD, patients with NPD were likely to be females ( Conclusions: Female gender and ALL were risk factors for NPD.

Indexed as

ALL, acute lymphoblastic leukemiaCancerCART, chimeric antigen receptor T-cellChimeric antigen receptor T cell therapyCI, confidence intervalDLBCL, diffuse large B-cell lymphomaFDA, Food and Drug AdministrationHMO, Health Maintenance OrganizationICD-10, International Classification of Disease Tenth RevisionIQR, interquartile rangeNeuropsychiatric disordersNeurotoxicityNIS, National Inpatient SampleNPD, neuropsychiatric disordersOncologyOR, odds ratioPMBCL, primary mediastinal large B-cell lymphomaPTSD, post-traumatic stress disorderSE, standard errorUS, United States

Identifiers

PMID36873581
PMCPMC9982636
OpenAlexW4321203706

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.