Evidence map›Paper›PMID 36873425›Full record

ArticleEClinicalMedicine2023

Association of preoperative COVID-19 and postoperative respiratory morbidity during the Omicron epidemic wave: the DROMIS-22 multicentre prospective observational cohort study.

Marc Garnier, Jean-Michel Constantin, Raphaël Cinotti, Chafia Daoui, Dimitri Margetis, Grégory Destruhaut, Cédric Cirenei, Eric Noll, Christophe Quesnel, Agnes Lecinq and 8 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in EClinicalMedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05336110 (Assessment of the Impact of the Postponement of Surgery on the Postoperative Morbidity After Sars-cov-2 Infection in 2022), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05336110 completednot on this map

Assessment of the Impact of the Postponement of Surgery on the Postoperative Morbidity After Sars-cov-2 Infection in 2022

TypeobservationalSponsorSociété Française d'Anesthésie et de RéanimationRan2022 to 2022Enrolled5,189ConditionsSARS CoV 2 InfectionArmsPostponing surgery
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

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  12. Cost-Effectiveness of Universal Asymptomatic Preoperative SARS-CoV-2 Polymerase Chain Reaction Screening: A Cost-Utility Analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 13 institutions in 2 countries.

Marc GarnierSorbonne Université, AP-HP, GRC29, DMU DREAM, Hôpital Tenon, Service d'Anesthésie-Réanimation et Médecine Périopératoire, 4 rue de la Chine, Paris 75020, France.
Jean-Michel ConstantinSorbonne Université, AP-HP, GRC29, DMU DREAM, Hôpital de la Pitié Salpêtrière, Service d'Anesthésie-Réanimation et Médecine Périopératoire, 91boulevard de l'Hôpital, Paris 75013, France.
Raphaël CinottiCHU Nantes, Nantes Université, Department of Anaesthesia and Critical Care, Hôtel Dieu, Nantes F-44000, France.
Chafia DaouiSFAR Research Network, Société Française d'Anesthésie Réanimation et médecine péri-opératoire (SFAR), 74 rue Raynouard, Paris 75016, France.
Dimitri MargetisSorbonne Université, AP-HP, GRC29, DMU DREAM, Hôpital de la Pitié Salpêtrière, Service d'Anesthésie-Réanimation et Médecine Périopératoire, 91boulevard de l'Hôpital, Paris 75013, France.
Grégory DestruhautClinique du Sport Bordeaux Mérignac, 4 rue Georges Négrevergne, Mérignac 33700, France.
Cédric CireneiPôle d'Anesthésie-Réanimation, Centre Hospitalier Universitaire de Lille, Boulevard du Professeur Jules Leclerc, Lille Cedex 59037, France.
Eric NollHôpitaux Universitaires de Strasbourg, Hôpital de Hautepierre, Service d'Anesthésie-Réanimation-Médecine Périopératoire, 1 Avenue Molière, Strasbourg, France.
Christophe QuesnelSorbonne Université, AP-HP, GRC29, DMU DREAM, Hôpital Tenon, Service d'Anesthésie-Réanimation et Médecine Périopératoire, 4 rue de la Chine, Paris 75020, France.
Agnes LecinqUniversité Paris-Saclay, APHP, Hôpital Antoine Béclère, Service d'Anesthésie, 157 rue de la Porte de Trivaux, Clamart 92140, France.
Sigismond LasockiDepartment of Anesthesiology and Critical Care Medicine, Centre Hospitalier Universitire d'Angers, 4 rue Larrey, Angers 49100, France.
Hélène CharbonneauDepartment of Anesthesiology and Intensive Care Unit, Clinique Pasteur, 45 avenue de Lombez, BP27617, Toulouse Cedex 03 31076, France.
Stanislas AbrardDepartment of Anesthesiology and Critical Care Medicine, Hospices Civils de Lyon, Edouard Herriot Hospital, 5 Place d'Arsonval, Lyon 69003, France.
Cyril QuemeneurSorbonne Université, AP-HP, GRC29, DMU DREAM, Hôpital de la Pitié Salpêtrière, Service d'Anesthésie-Réanimation et Médecine Périopératoire, 91boulevard de l'Hôpital, Paris 75013, France.
Bruno PasteneAix Marseille Université, Assistance Publique-Hôpitaux Universitaire de Marseille, Hôpital Nord, Service d'Anesthésie et de Réanimation, Chemin de Bourrely, Marseille 13015, France.
Nathanaël LapidusSorbonne Université, Inserm, Institut Pierre Louis d'Epidémiologie et de Santé Publique, AP-HP, Saint-Antoine Hospital, Public Health Department, Paris F75012, France.
Marc LeoneAix Marseille Université, Assistance Publique-Hôpitaux Universitaire de Marseille, Hôpital Nord, Service d'Anesthésie et de Réanimation, Chemin de Bourrely, Marseille 13015, France.
DROMIS-22 Study Group and the SFAR Research Network
Sorbonne Université · FRAix-Marseille Université · FRInserm · FRUniversité Clermont Auvergne · FRHôpitaux Universitaires de Strasbourg · FRAssistance Publique – Hôpitaux de Paris · FRCentre Hospitalier Universitaire d'Angers · FRCentre Hospitalier Universitaire de Lille · FRClinique du Sport · FRClinique Pasteur · FRHospices Civils de Lyon · FRSociété Française d'Allergologie · FRUniversité Paris-Saclay · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Preoperative COVID-19 has been associated with excess postoperative morbi-mortality. Consequently, guidelines were developed that recommended the postponement of surgery for at least 7 weeks after the infection. We hypothesised that vaccination against the SARS-CoV-2 and the large predominance of the Omicron variant attenuated the effect of a preoperative COVID-19 on the occurrence of postoperative respiratory morbidity. Methods: We conducted a prospective cohort study in 41 French centres between 15 March and 30 May 2022 (ClinicalTrials NCT05336110), aimed at comparing the postoperative respiratory morbidity between patients with and without preoperative COVID-19 within 8 weeks prior to surgery. The primary outcome was a composite outcome combining the occurrence of pneumonia, acute respiratory failure, unexpected mechanical ventilation, and pulmonary embolism within the first 30 postoperative days. Secondary outcomes were 30-day mortality, hospital length-of-stay, readmissions, and non-respiratory infections. The sample size was determined to have 90% power to identify a doubling of the primary outcome rate. Adjusted analyses were performed using propensity score modelling and inverse probability weighting. Findings: Of the 4928 patients assessed for the primary outcome, of whom 92.4% were vaccinated against the SARS-CoV-2, 705 had preoperative COVID-19. The primary outcome was reported in 140 (2.8%) patients. An 8-week preoperative COVID-19 was not associated with increased postoperative respiratory morbidity (odds ratio 1.08 [95% CI 0.48-2.13]; Interpretation: In our Omicron-predominant, highly immunised population undergoing general surgery, a preoperative COVID-19 was not associated with increased postoperative respiratory morbidity. Funding: The study was fully funded by the French Society of Anaesthesiology and Intensive Care Medicine (SFAR).

Indexed as

Acute respiratory failureAnaesthesiaCOVID-19Perioperative riskPostoperative pneumoniaPrognosisRespiratory complicationsSurgery

Identifiers

PMID36873425
PMCPMC9975647
OpenAlexW4322755627

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.