ReviewHeart rhythm O22023
The value of functional substrate mapping in ventricular tachycardia ablation.
Review in Heart rhythm O2, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Dominant Frequency Mapping as a Functional Tool for Substrate-Guided Ventricular Tachycardia Ablation.Journal of cardiovascular electrophysiology · 2026Article
- Feasibility of functional substrate mapping with a novel lattice-tip catheter: Implications for ventricular tachycardia ablation.Heart rhythm O2 · 2026Article
- Functional Substrate Mapping in Ablation for Scar-Related Ventricular Tachycardia.Reviews in cardiovascular medicine · 2026Review
- Successful Substrate-Guided Ablation of Ventricular Tachycardia Storm in Acute Heart Failure Without Mechanical Circulatory Support.JACC. Case reports · 2025Article
- Outcomes following catheter ablation for structural ventricular tachycardia stratified by left ventricular ejection fraction: A retrospective cohort study.Heart rhythm O2 · 2025Article
- Impact of atrial functional substrate in patients with atrial fibrillation: The potential utility of decremental evoked potential mapping in the atrium.Heart rhythm O2 · 2025Article
- To the Editor- Functional substrate mapping of ventricular arrhythmia.Heart rhythm O2 · 2025Article
- Catheter Ablation for Ventricular Tachycardias: Current Status and Future Perspectives.Journal of clinical medicine · 2024Article
- Near-field detection and peak frequency metric for substrate and activation mapping of ventricular tachycardias in two- and three-dimensional circuits.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024Article
- Technological advances in ventricular tachycardia catheter ablation: the relentless quest for novel solutions to old problems.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024Review
- Contemporary management of ventricular arrhythmias in heart failure.American journal of cardiovascular disease · 2023Review
Corrections and comments
- Erratum issuedCorrigendum.2025
Authors and funding
21 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the setting of structural heart disease, ventricular tachycardia (VT) is typically associated with a re-entrant mechanism. In patients with hemodynamically tolerated VTs, activation and entrainment mapping remain the gold standard for the identification of the critical parts of the circuit. However, this is rarely accomplished, as most VTs are not hemodynamically tolerated to permit mapping during tachycardia. Other limitations include noninducibility of arrhythmia or nonsustained VT. This has led to the development of substrate mapping techniques during sinus rhythm, eliminating the need for prolonged periods of mapping during tachycardia. Recurrence rates following VT ablation are high; therefore, new mapping techniques for substrate characterization are required. Advances in catheter technology and especially multielectrode mapping of abnormal electrograms has increased the ability to identify the mechanism of scar-related VT. Several substrate-guided approaches have been developed to overcome this, including scar homogenization and late potential mapping. Dynamic substrate changes are mainly identified within regions of myocardial scar and can be identified as local abnormal ventricular activities. Furthermore, mapping strategies incorporating ventricular extrastimulation, including from different directions and coupling intervals, have been shown to increase the accuracy of substrate mapping. The implementation of extrastimulus substrate mapping and automated annotation require less extensive ablation and would make VT ablation procedures less cumbersome and accessible to more patients.
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