Evidence map›Paper›PMID 36873291›Full record

ArticleAfrican journal of laboratory medicine2023

Alternative methods for calculating percentage haemolysis of red cell concentrates in peripheral blood banks in Sri Lanka.

Caroline A Fernando, Deklanji T Dissanayake, Uththara I Hewamana, Shyamini Rathnaweera, Wickrama A Samanthilake, Ranga Tudugala, Kithsiri B Jayasekara, Kumudu Kuruppu

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Article in African journal of laboratory medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Caroline A FernandoDepartment of Medical Laboratory Sciences, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Werahera, Sri Lanka.ORCID 0000-0002-7581-7838
Deklanji T DissanayakeDepartment of Medical Laboratory Sciences, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Werahera, Sri Lanka.ORCID https://orcid.org/0000-0002-0397-3030
Uththara I HewamanaDepartment of Medical Laboratory Sciences, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Werahera, Sri Lanka.ORCID https://orcid.org/0000-0002-7495-6879
Shyamini RathnaweeraDepartment of Medical Laboratory Sciences, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Werahera, Sri Lanka.ORCID https://orcid.org/0000-0002-8860-9624
Wickrama A SamanthilakeDepartment of Quality Management, National Blood Center, Narahenpita, Sri Lanka.ORCID https://orcid.org/0000-0002-4604-1030
Ranga TudugalaDepartment of Radiography and Radiotherapy, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Werahera, Sri Lanka.ORCID https://orcid.org/0000-0002-0145-7825
Kithsiri B JayasekaraDepartment of Medical Laboratory Sciences, Faculty of Allied Health Sciences, General Sir John Kotelawala Defence University, Werahera, Sri Lanka.ORCID https://orcid.org/0000-0002-2309-2548
Kumudu KuruppuDepartment of Quality Management, National Blood Center, Narahenpita, Sri Lanka.ORCID https://orcid.org/0000-0001-9270-5320
General Sir John Kotelawala Defence University · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Haemolysis - one of the major limiting factors of red cell concentrate quality - must be measured as a quality-monitoring requirement. According to international quality standards, percentage haemolysis must be monitored in 1.0% of red cell concentrates produced monthly and maintained under 0.8%. Objective: This study assessed three alternative methods for determining plasma haemoglobin concentration in peripheral blood banks that lack a plasma or low haemoglobin photometer - the gold-standard method - in Sri Lanka. Methods: A standard haemolysate was prepared using an unexpired whole blood pack of normal haemoglobin concentration. A concentration series from 0.1 g/dL to 1.0 g/dL was prepared by diluting portions of standard haemolysate with saline. The alternative methods, namely visual haemoglobin colour scale, spectrophotometric calibration graph, and standard haemolysate capillary tube comparison, were designed using this concentration series and were used to test red cell concentrates received at the Quality Control Department of the National Blood Center, Sri Lanka, from February 2021 to May 2021. Results: A strong correlation was observed between the haemoglobin photometer method and the alternative methods ( Conclusion: All three alternative methods are recommended for use in peripheral blood banks. The standard haemolysate capillary tube comparison method was the best model.

Indexed as

blood bankscapillary tube comparisonhaemoglobin colour scalepercentage haemolysisred cell concentrate

Identifiers

PMID36873291
PMCPMC9982517
OpenAlexW4321498733

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.