ReviewExposure and health2023
To Waste or Not to Waste: Questioning Potential Health Risks of Micro- and Nanoplastics with a Focus on Their Ingestion and Potential Carcinogenicity.
Review in Exposure and health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The impact of microplastics on the mice gut microbiome: a meta-analysis.Scientific reports · 2026Pooled it
- Size-dependent plastic exposure disrupts macrophage function and tissue-specific metabolism.Nature metabolism · 2026Article
- In Silico Study of Enzymatic Degradation of Bioplastic by Microalgae: An Outlook on Microplastic Environmental Impact Assessment, Challenges, and Opportunities.Molecular biotechnology · 2026Review
- Nanoplastic Pollution of Human Bronchoalveolar Lavage Probed Based on Tip-Enhanced Raman Scattering.Sensors (Basel, Switzerland) · 2026Article
- Tracking of [Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- From plastic spine hypothesis to decision-grade evidence: building a translational exposome framework for spine research.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Ingested microplastics and gastrointestinal health: a comprehensive review of their role in gut inflammation and dysbiosis.Annals of medicine and surgery (2012) · 2026Article
- The "plastic spine" phenotype and the spine exposome: emerging links between micro- and nanoplastics and spinal disorders.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Method for label-free & non-destructive detection of microplastics in human formalin-fixed paraffin-embedded tissue sections.Scientific reports · 2025Article
- Global Research Trends on Nanoplastics in Food: A Bibliometric Analysis of Human Health Concerns.Foods (Basel, Switzerland) · 2025Article
- Detection of Unlabeled Polystyrene Micro- and Nanoplastics in Mammalian Tissue by Optical Photothermal Infrared Spectroscopy.Analytical chemistry · 2025Article
- Metabolic Dysfunction-Associated Steatotic Liver Disease Induced by Microplastics: An Endpoint in the Liver-Eye Axis.International journal of molecular sciences · 2025Review
- Nanoplastics: Immune Impact, Detection, and Internalization after Human Blood Exposure by Single-Cell Mass Cytometry.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Towards a 'theory of change' for ocean plastics: a socio-oceanography approach to the global challenge of plastic pollution.Microplastics and nanoplastics · 2025Review
- Microplastics - A Growing Concern as Carcinogens in Cancer Etiology: Emphasis on Biochemical and Molecular Mechanisms.Cell biochemistry and biophysics · 2024Review
- The adsorption of drugs on nanoplastics has severe biological impact.Scientific reports · 2024Article
- Multifaceted Aquatic Environmental Differences between Nanoplastics and Microplastics: Behavior and Fate.Environment & health (Washington, D.C.) · 2024Review
- Embracing Nature's Clockwork: Crafting Plastics for Degradation in Plant Agricultural Systems.ACS materials Au · 2024Review
- Numerical Study towards In Vivo Tracking of Micro-/Nanoplastic Based on X-ray Fluorescence Imaging.Biomedicines · 2024Article
- Health effects of microplastics and nanoplastics: review of published case reports.Environmental analysis, health and toxicology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Micro- and nanoplastics (MNPs) are recognized as emerging contaminants, especially in food, with unknown health significance. MNPs passing through the gastrointestinal tract have been brought in context with disruption of the gut microbiome. Several molecular mechanisms have been described to facilitate tissue uptake of MNPs, which then are involved in local inflammatory and immune responses. Furthermore, MNPs can act as potential transporters ("vectors") of contaminants and as chemosensitizers for toxic substances ("Trojan Horse effect"). In this review, we summarize current multidisciplinary knowledge of ingested MNPs and their potential adverse health effects. We discuss new insights into analytical and molecular modeling tools to help us better understand the local deposition and uptake of MNPs that might drive carcinogenic signaling. We present bioethical insights to basically re-consider the "culture of consumerism." Finally, we map out prominent research questions in accordance with the Sustainable Development Goals of the United Nations.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.