Evidence map›Paper›PMID 36873174›Full record

ArticleActa pharmaceutica Sinica. B2023

Precise assembly of inside-out cell membrane camouflaged nanoparticles

Xiaolin Zhang, Xueyan Zhen, Yixuan Yang, Quan Feng, Wanqing Yuan, Xiaoyu Xie

Abstract read
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaolin ZhangSchool of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, China.
Xueyan ZhenSchool of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, China.
Yixuan YangSchool of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, China.
Quan FengSchool of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, China.
Wanqing YuanSchool of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, China.
Xiaoyu XieSchool of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell membrane camouflaged nanoparticles have been widely used in the field of drug leads discovery attribute to their unique biointerface targeting function. However, random orientation of cell membrane coating does not guarantee effective and appropriate binding of drugs to specific sites, especially when applied to intracellular regions of transmembrane proteins. Bioorthogonal reactions have been rapidly developed as a specific and reliable method for cell membrane functionalization without disturbing living biosystem. Herein, inside-out cell membrane camouflaged magnetic nanoparticles (IOCMMNPs) were accurately constructed

Indexed as

Alkynyl functionalizationBioorthogonal reactionsCell membrane camouflaged nanoparticlesDrug leads discoveryInside-out cell membrane coatingMagnetic nanoparticlesPrecise assemblyTraditional Chinese medicine

Identifiers

PMID36873174
PMCPMC9979189

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.