Evidence map›Paper›PMID 36873078›Full record

ArticleClinical case reports2023

A rare adverse event of atorvastatin inducing leukocytoclastic vasculitis with ANCA-negative (Anti-Neutrophil cytoplasmic antibody) case report and literature review.

Nehemias Guevara-Rodriguez, Mailing Flores-Chang, Akhila Chilakala, Jose Contreras, Paula Perdomo, Gandrabur Liliya

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Nehemias Guevara-RodriguezDepartment of Medicine, Internal Medicine St. Barnabas Hospital Health System Bronx New York USA.ORCID https://orcid.org/0000-0003-3808-0803
Mailing Flores-ChangDepartment of Medicine, Internal Medicine St. Barnabas Hospital Health System Bronx New York USA.
Akhila ChilakalaCUNY School of Medicine, Medical school in New York City New York New York USA.
Jose ContrerasDepartment of Medicine, Internal Medicine St. Barnabas Hospital Health System Bronx New York USA.
Paula PerdomoDepartment of Medicine, Internal Medicine St. Barnabas Hospital Health System Bronx New York USA.
Gandrabur LiliyaInternal Medicine, Department of Rheumatology St. Barnabas Hospital Health System Bronx New York USA.
St. Barnabas Hospital · USCUNY School of Law · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leukocytoclastic vasculitis is an entity associated with drugs, infections, cryoglobulinemia, and connective tissue diseases but can also be idiopathic, systemic, or organ localized. Moreover, LCV associated with drugs is a rare disorder. When it is present usually has an elevation of anti-neutrophil cytoplasmic antibody, most likely anti-myeloperoxidase, which can be helpful to orient the diagnosis. We are presenting a 55-year-old female with a past medical history of diabetes mellitus (DM) and hyperlipidemia (HLD) who presented with a painful and pruritic rash localized in the abdomen and lower extremities that started 1 week after initiated atorvastatin for management of hyperlipidemia. This is the first case ever reported of leukocytoclastic vasculitis ANCA negative associated with atorvastatin, to our best knowledge.

Indexed as

ANCAatorvastatindrug reactionLeukocytoclastic vasculitistreatmentvasculitis

Identifiers

PMID36873078
PMCPMC9981573
OpenAlexW4323050201

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.