Evidence map›Paper›PMID 36873076›Full record

ArticleClinical case reports2023

Successful treatment with bortezomib for POEMS syndrome, overcoming complicated severe heart block.

Yuichi Nakamura, Yoshihiro Itoh, Naoki Wakimoto, Ryu Kanno, Shinichirou Iida, Keiji Yamamoto

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yuichi NakamuraDepartment of Hematology Saitama Medical University Hospital Moroyama Japan.ORCID https://orcid.org/0000-0001-9518-8453
Yoshihiro ItohDepartment of Hematology Saitama Medical University Hospital Moroyama Japan.
Naoki WakimotoDepartment of Hematology Saitama Medical University Hospital Moroyama Japan.
Ryu KannoDepartment of Cardiovascular Medicine Saitama Medical University Hospital Moroyama Japan.
Shinichirou IidaDepartment of Cardiovascular Medicine Saitama Medical University Hospital Moroyama Japan.
Keiji YamamotoDepartment of Cardiovascular Medicine Saitama Medical University Hospital Moroyama Japan.
Saitama Medical University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac bradyarrhythmia and conduction disorder may be rare, but recurrent adverse events caused by bortezomib. Here we report a case with POEMS syndrome presenting severe heart block after bortezomib plus dexamethasone therapy. After permanent pacemaker implantation, bortezomib was restarted and maintained, resulting in sustained complete response for POEMS syndrome.

Indexed as

AV blockbortezomibheart blockPOEMS syndrome

Identifiers

PMID36873076
PMCPMC9979967
OpenAlexW4323066675

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.