ReviewFrontiers in allergy2023
Immunomodulatory role of oral microbiota in inflammatory diseases and allergic conditions.
Review in Frontiers in allergy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 42 citations in OpenAlex.
- Pilot Study of Oral Microbiome and Psychoneurological Symptom Cluster in Breast Cancer.Nursing research · 2026Article
- The oral microbiota in oral squamous cell carcinoma: unravelling mechanisms and clinical potential.Cancer cell international · 2026Review
- Association between dental plaque index and COVID-19 severity: a cross-sectional study in a conflict-affected humanitarian setting.BMC oral health · 2026Article
- Impact of e-cigarette vaping on the immune system across the body.Physiological reviews · 2026Review
- Oral Barrier Immunometabolism in Chronic Low-Grade Inflammation: Molecular Mechanisms and Systemic Implications.International journal of molecular sciences · 2026Review
- Oral Self-Care as a Preventive Strategy in Medicated Older Adults: Biological Mechanisms, Genetic Susceptibility, and Public Health Implications.Healthcare (Basel, Switzerland) · 2026Review
- Periodontitis-Induced Immune Reprogramming: Implications for Cancer Immunotherapy Response.Biomedicines · 2026Review
- Association of asthma and anti-asthmatic therapy with oral health and microbiota alterations in children - a cross-sectional study.BMC pediatrics · 2026Article
- The Oral Microbiota: Implications in Mucosal Health and Systemic Disease-Crosstalk with Gut and Brain.Cells · 2026Review
- Characterize Oral-to-Blood Microbial DNA Translocation in Individuals with Cocaine Use Disorder.bioRxiv : the preprint server for biology · 2026Article
- Supragingival plaque microbiome features in allergic rhinitis and allergic asthma and their association with dental caries: a cross-sectional study.Journal of oral microbiology · 2026Article
- Baseline characteristics of the HOMINY (human papillomavirus, human immunodeficiency virus, and oral microbiota interplay in Nigerian youth) prospective longitudinal cohort.Frontiers in oral health · 2026Article
- Bidirectional Mendelian randomization between oral microbiota and allergic rhinitis in East Asian populations.Journal of oral microbiology · 2026Article
- Applications of extracellular vesicles in tissue regeneration: a narrative review.Frontiers in bioengineering and biotechnology · 2026Review
- Next-Generation Probiotics in Allergy Therapy: Scientific Evidence and Clinical Applications.Anti-inflammatory & anti-allergy agents in medicinal chemistry · 2026Review
- Diabesity and Oral Immunity: Exploring the Interconnection.Advances in experimental medicine and biology · 2026Review
- Oral microbiota and urinary system diseases: from mechanistic insights to clinical implications-a comprehensive review.Frontiers in dental medicine · 2026Review
- Desquamative Gingivitis and the Oral Microbiome: Insights into Immune-Microbial Interactions in Mucosal Inflammation.Dentistry journal · 2025Review
- Oral microbiome and inflammatory bowel disease: New understanding and call to action.World journal of gastroenterology · 2025Review
- Animal farming and the oral microbiome in the Agricultural Health Study.Environmental research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, the interplay between oral microbiota and systemic disease has gained attention as poor oral health is associated with several pathologies. The oral microbiota plays a role in the maintenance of overall health, and its dysbiosis influences chronic inflammation and the pathogenesis of gum diseases. Periodontitis has also been associated with other diseases and health complications such as cancer, neurogenerative and autoimmune disorders, chronic kidney disease, cardiovascular diseases, rheumatic arthritis, respiratory health, and adverse pregnancy outcomes. The host microbiota can influence immune cell development and immune responses, and recent evidence suggests that changes in oral microbiota composition may also contribute to sensitization and the development of allergic reactions, including asthma and peanut allergies. Conversely, there is also evidence that allergic reactions within the gut may contribute to alterations in oral microbiota composition. Here we review the current evidence of the role of the oral microbiota in inflammatory diseases and health complications, as well as its future relevance in improving health and ameliorating allergic disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.