Evidence map›Paper›PMID 36872780›Full record

ArticleJournal of Alzheimer's disease : JAD2023

The Effect of Self-Reported Visual Impairment and Sleep on Cognitive Decline: Results of the Hispanic Community Health Study/Study of Latinos.

Elizabeth Mahanna-Gabrielli, Sayaka Kuwayama, Wassim Tarraf, Sonya Kaur, Delia Cabrera DeBuc, Jianwen Cai, Martha L Daviglus, Charlotte E Joslin, David J Lee, Carlos Mendoza-Santiesteban and 4 more

Open access · greenAbstract read
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Elizabeth Mahanna-GabrielliUniversity of Miami Miller School of Medicine, Miami, FL, USA.
Sayaka KuwayamaUniversity of California, San Diego, La Jolla, CA, USA.
Wassim TarrafWayne State University, Detroit, MI, USA.
Sonya KaurUniversity of Miami Miller School of Medicine, Miami, FL, USA.
Delia Cabrera DeBucBascom Palmer Eye Institute, University of Miami, Miami, FL, USA.
Jianwen CaiUniversity of North Carolina, Chapel Hill, NC, USA.
Martha L DaviglusUniversity of Illinois at Chicago, Chicago, IL, USA.
Charlotte E JoslinUniversity of Illinois, Chicago, IL, USA.
David J LeeUniversity of Miami Miller School of Medicine, Miami, FL, USA.
Carlos Mendoza-SantiestebanBascom Palmer Eye Institute, University of Miami, Miami, FL, USA.
Ariana M StickelUniversity of California, San Diego, La Jolla, CA, USA.
Diane ZhengUniversity of Miami Miller School of Medicine, Miami, FL, USA.
Hector M GonzálezUniversity of California, San Diego, La Jolla, CA, USA.
Alberto R RamosUniversity of Miami Miller School of Medicine, Miami, FL, USA.
University of Miami · USUniversity of California, San Diego · USUniversity of Illinois Chicago · USUniversity of North Carolina at Chapel Hill · USWayne State University · US

Funding

UCSD Shiley-Marcos Alzheimer's Disease Research Center P30P30AG062429 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Mark W Bondi · 2019 to 2026
$34.9M
Hispanic Community Health Study - NIDCDN01HC65235 · NHLBI · YESHIVA UNIVERSITY · PI KAPLAN, ROBERT · 2007 to 2012
$16.0M
OTHER FUNCTIONS - R&D - HISPANIC COMMUNITY HEALTH STUDYN01HC65233 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CAI, JAIWEN · 2007 to 2012
$15.1M
MRI Measures of Cerebrovascular Injury and AD Atrophy in a Study of LatinosRF1AG054548 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DECARLI, CHARLES, GONZALEZ, HECTOR M · 2017 to 2017
$14.7M
Sleep in Neurocognitive Aging and Alzheimers Research (SANAR)R01AG067568 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Alberto Rafael Ramos · 2021 to 2026
$13.7M
HISPANIC COMMUNITY HEALTH STUDY - FIELD CENTERN01HC65236 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DIVIGLUS, MARTHA · 2007 to 2012
$13.4M
HISPANIC COMMUNITY HEALTH STUDY - FIELD CENTERN01HC65234 · NHLBI · UNIVERSITY OF MIAMI CORAL GABLES · PI SCHNEIDERMAN, NEIL · 2007 to 2012
$13.1M
HISPANIC COMMUNITY HEALTH STUDY - FIELD CENTERN01HC65237 · NHLBI · SAN DIEGO STATE UNIVERSITY · PI TALAVERA, GREGORY · 2007 to 2013
$12.4M
San Diego Resource Center for advancing Alzheimer's Research in Minority Seniors (ARMS)P30AG059299 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ALISON AHERN MOORE · 2018 to 2026
$7.4M
Phenotypic and Molecular Signatures for Sleep Apnea and Related MorbiditiesR35HL135818 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI REDLINE, SUSAN S. · 2017 to 2023
$7.2M
Neurocognitive aging, MCI and Alzheimer's disease DNA methylation among diverse LatinosRF1AG061022 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FORNAGE, MYRIAM, GONZALEZ, HECTOR M · 2019 to 2019
$6.6M
Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA)R01AG048642 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GONZALEZ, HECTOR M · 2015 to 2019
$5.7M
NHLBI NIH HHS N01HC65233NHLBI NIH HHS N01HC65234NHLBI NIH HHS N01HC65235NHLBI NIH HHS N01HC65236NHLBI NIH HHS N01HC65237NHLBI NIH HHS R01 HL153814NHLBI NIH HHS R01 HL161012NHLBI NIH HHS R21 HL145425NHLBI NIH HHS R35 HL135818NIA NIH HHS P30 AG059299NIA NIH HHS P30 AG062429NIA NIH HHS R01 AG048642NIA NIH HHS R01 AG067568NIA NIH HHS R21 AG056952NIA NIH HHS R21 AG070644NIA NIH HHS RF1 AG054548NIA NIH HHS RF1 AG061022
6 · The paper itself

Abstract

backgroundVisual impairment could worsen sleep/wake disorders and cognitive decline.

objectiveTo examine interrelations among self-reported visual impairment, sleep, and cognitive decline in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) Miami-site.

methodHCHS/SOL Miami-site participants ages 45-74 years (n = 665) at Visit-1, who returned for cognitive test 7-years later (SOL-INCA). Participants completed the National Eye Institute Visual Functioning Questionnaire (NEI-VFQ), validated sleep questionnaires and test for obstructive sleep apnea (OSA) at Visit-1. We obtained verbal episodic learning and memory, verbal fluency, processing speed, and executive functioning at Visit-1 and at SOL-INCA. Processing speed/executive functioning were added to SOL-INCA. We examined global cognition and change using a regression-based reliable change index, adjusting for the time lapse between Visit-1 and SOL-INCA. We used regression models to test whether 1) persons with OSA, self-reported sleep duration, insomnia, and sleepiness have an increased risk for visual impairment, 2a) visual impairment is associated with worse cognitive function and/or decline, and 2b) sleep disorders attenuate these associations.

resultSleepiness (β= 0.04; p < 0.01) and insomnia (β= 0.04; p < 0.001) were cross-sectionally associated with visual impairment, adjusting for sociodemographic characteristics, behavioral factors, acculturation, and health conditions. Visual impairment was associated with lower global cognitive function at Visit-1 (β= -0.16; p < 0.001) and on average 7-years later (β= -0.18; p < 0.001). Visual impairment was also associated with a change in verbal fluency (β= -0.17; p < 0.01). OSA, self-reported sleep duration, insomnia, and sleepiness did not attenuate any of the associations.

conclusionSelf-reported visual impairment was independently associated with worse cognitive function and decline.

Indexed as

Cognitive DysfunctionHispanic or LatinoSleep Apnea, ObstructiveSleep Initiation and Maintenance DisordersVision DisordersAgedHumansMiddle AgedSelf ReportSleepSleep DurationSleepinessSpeech DisordersCognitive declinehealth disparitiesHispanic/Latinossleep disordersvisual impairment

Identifiers

PMID36872780
PMCPMC10792435
OpenAlexW4323040684

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.