ReviewEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2023
Clinico-histopathological review of 255 patients who underwent parotidectomy for pleomorphic adenoma: a 10-year retrospective study-a proposal for an optimal diagnostic and therapeutic algorithm for patients with recurrent pleomorphic adenoma.
Review in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 20 citations in OpenAlex.
- Clinicopathological Characteristics and Postoperative Outcomes Following Parotidectomy: A Ten-Year Retrospective Study from a Tertiary Center.Diseases (Basel, Switzerland) · 2026Article
- Investigating the Relationship Human Parvovirus B19 Infection in Benign and Malignant Salivary Gland Tumors.Journal of dentistry (Shiraz, Iran) · 2026Article
- Value of Routine Follow-Up After Pleomorphic Adenoma Surgery.Journal of clinical medicine · 2026Article
- A comprehensive model with dual plane ultrasound based deep learning radiomics to distinguish parotid pleomorphic adenoma from Warthin tumor.Frontiers in oncology · 2026Article
- Systematic Review and Case Report on the Surgical Management of Pleomorphic Adenomas: Lessons on Recurrence and Error Prevention.Journal of clinical medicine · 2025Review
- Machine learning model for preoperative classification of stromal subtypes in salivary gland pleomorphic adenoma based on ultrasound histogram analysis.BMC oral health · 2025Article
- Use of the SMAS Flap in Benign Parotid Gland Surgery: Review and 5 Years Experience.Journal of maxillofacial and oral surgery · 2025Article
- Local anaesthesia with conscious sedation in parotid gland tumour resection: a retrospective review.BMC oral health · 2024Article
- Extracapsular Dissection Versus Traditional Parotid Surgery: A Comprehensive Review of Techniques and Outcomes.Cureus · 2024Review
- Long-term follow-up and prognostic analysis of parotid tumors in children and adolescents.Laryngoscope investigative otolaryngology · 2024Article
- Retrospective Analysis of Histopathological Reports of Salivary Gland Pleomorphic Adenomas in Tanzania.The East African health research journal · 2024Article
- Deep learning based ultrasound analysis facilitates precise distinction between parotid pleomorphic adenoma and Warthin tumor.Frontiers in oncology · 2024Article
- When pathologists are lost along the way.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Article
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6 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposePleomorphic adenoma (mixed tumor) is the most common neoplasm of the parotid gland and one of the most frequent types of salivary gland tumor, generally with benign behavior and relatively slow growing. The adenomas could arise from the superficial, deep or from both superficial and deep parotid's lobes.
methodsThe aim of this review is to retrospectively analyze the surgical management of patients with pleomorphic adenoma of the parotid gland performed at the Department of Otorhinolaryngology (Department of Sense Organs of "Azienda Policlinico Umberto I" in Rome), from 2010 to 2020, with a focus on the percentage of recurrence and on the complication related to surgery to suggest an optimal diagnostic and therapeutic algorithm for patients with recurrent pleomorphic adenoma. The analysis of the complications observed in case of different surgical approaches was performed using the X
resultsThe choice of a surgical approach (superficial parotidectomy-SP, total parotidectomy-TP, extracapsular dissection-ECD) depends on several elements, such as the location and the size of the adenoma, the availability of existing technical facilities and the professional experience of the surgeon. A transient facial palsy was present in 37.6%, 2.7% reported a permanent facial nerve palsy, 1.6% developed a salivary fistula, 1.6% a post-operative bleeding and 2.3% showed Frey Syndrome.
conclusionThe surgical management of this benign lesion is required, even in asymptomatic cases, to prevent the progressive growing and to reduce the risk of malignant transformation. The goal of surgical excision is to obtain the complete resection to minimize the risk of tumor recurrence and avoiding facial nerve disability. Therefore, an accurate preoperative study of the lesion and the choice of the most appropriate surgical treatment are essential to minimize the rate of recurrence.
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