Evidence map›Paper›PMID 36872138›Full record

Trial reportEpilepsy & behavior : E&B2023

Sense of control, selective attention, cognitive inhibition, and psychosocial outcomes after Retraining and Control Therapy (ReACT) in pediatric functional seizures.

Lindsay Stager, Christina Mueller, Skylar Morriss, Jerzy P Szaflarski, Aaron D Fobian

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Epilepsy & behavior : E&B, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lindsay StagerUniversity of Alabama at Birmingham, Department of Psychology, United States.
Christina MuellerUniversity of Alabama at Birmingham, Department of Neurology, United States.
Skylar MorrissUniversity of Alabama at Birmingham, Department of Psychology, United States.
Jerzy P SzaflarskiUniversity of Alabama at Birmingham, Department of Neurology, United States; University of Alabama at Birmingham, Departments Neurosurgery and Neurobiology and the UAB Epilepsy Center, United States.
Aaron D FobianUniversity of Alabama at Birmingham, Department of Psychiatry and Behavioral Neurobiology, United States. Electronic address: afobian@uabmc.edu.
University of Alabama at Birmingham · US

Funding

Retraining and Control Therapy (ReACT): Sense of control and catastrophic symptom expectations as targets of a cognitive behavioral treatment for pediatric psychogenic non-epileptic seizures (PNES)R61MH127155 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FOBIAN, AARON D · 2021 to 2022
$1.4M
NIMH NIH HHS R61 MH127155
6 · The paper itself

Abstract

backgroundDifferences in sense of control, cognitive inhibition, and selective attention in pediatric functional seizures (FS) versus matched controls implicate these as potential novel treatment targets. Retraining and Control Therapy (ReACT), which targets these factors, has been shown in a randomized controlled trial to be effective in improving pediatric FS with 82% of patients having complete symptom remission at 60 days following treatment. However, post-intervention data on sense of control, cognitive inhibition, and selective attention are not yet available. In this study, we assess changes in these and other psychosocial factors after ReACT.

methodsChildren with FS (N = 14, M

resultsAwareness that control was manipulated in the turbulence condition of the MAT increased at post-1 vs. pre- (p = 0.02, η

conclusionSense of control improved after ReACT, and this improvement was proportional to a decrease in FS, suggesting this as a possible mechanism by which ReACT treats pediatric FS. Selective attention and cognitive inhibition were significantly increased 60 days after ReACT. The lack of improvement in QOL after controlling for change in FS suggests QOL changes may be mediated by decreases in FS. ReACT also improved general somatic symptoms independent of FS changes.

Indexed as

Medically Unexplained SymptomsQuality of LifeAttentionChildCognitionFemaleHumansInternal-External ControlMaleSeizuresAgencyCognitive inhibitionControlFunctional neurological disorderFunctional seizuresSelective attention

Identifiers

PMID36872138
PMCPMC10164678
OpenAlexW4323034279

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.