Evidence map›Paper›PMID 36871275›Full record

Trial reportGeneral thoracic and cardiovascular surgery2023

A series of experiences with TissuePatch™ for alveolar air leak after pulmonary resection.

Takahiro Homma

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in General thoracic and cardiovascular surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Takahiro HommaDivision of Thoracic Surgery, Kurobe City Hospital, 1108-1 Mikkaichi, Kurobe, Toyama, 938-8502, Japan. hommat.tym@gmail.com.ORCID http://orcid.org/0000-0001-5117-5570

Funding

University of Toyama the Toyama Prefecture Citizens' Personal Development Foundation (TomiHito #52).
6 · The paper itself

Abstract

objectivesProlonged air leak after pulmonary resection strongly influences chest tube duration and hospitalization. This prospective study aimed to report a series of experiences with a synthetic sealant (TissuePatch™) and compare them with a combination covering method (polyglycolic acid sheet + fibrin glue) for air leaks after pulmonary surgery.

methodsWe included 51 patients (age: 20-89 years) who underwent lung resection. Patients who presented with alveolar air leak during the intraoperative water sealing test were randomly assigned to the TissuePatch™ or combination covering method groups. The chest tube was removed when there was no air leak over a period of 6 h, and no active bleeding under continuous monitoring using a digital drainage system. The chest tube duration was assessed, and various perioperative factors (such as the index of prolonged air leak score) were evaluated.

resultsTwenty (39.2%) patients developed intraoperative air leak; ten patients received TissuePatch™; and one patient who was receiving TissuePatch™ switched to the combination covering method because of broken TissuePatch™. The chest tube duration, index of prolonged air leak score, prolonged air leak, other complications, and postoperative hospitalization in both groups were similar. No TissuePatch™-related adverse events were reported.

conclusionsResults from the use of TissuePatch™ were almost similar to those associated with the use of combination covering method in preventing prolonged postoperative air leak after pulmonary resection. Randomized, double-arm studies are required to confirm the efficacy of TissuePatch™ observed during this study.

Indexed as

PneumonectomyPostoperative ComplicationsAdultAgedAged, 80 and overChest TubesDrainageFibrin Tissue AdhesiveHumansMiddle AgedProspective StudiesYoung AdultFibrin Tissue AdhesiveAir leakLung resectionThoracic surgeryVideo-assisted thoracoscopic surgeryWater sealing test

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.