Evidence map›Paper›PMID 36871053›Full record

ArticleBMC veterinary research2023

Wavy changes in the whiskers of domestic cats are correlated with feline leukemia virus infection.

Masataka Morishita, Yuji Sunden, Misaki Horiguchi, Hirosei Sakoya, Mana Yokogawa, Hiroyuki Ino, Satoshi Une, Mutsumi Kawata, Taisei Hosoido, Takehito Morita

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC veterinary research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Masataka MorishitaNiihama Animal Hospital, 2-1-11 Wakamizu Niihama, Ehime, 792-0017, Japan.
Yuji SundenLaboratory of Veterinary Pathology, Joint Department of Veterinary Medicine, Faculty of Agriculture, Tottori University, 4-101 Koyama-Minami, Tottori, 680-8553, Japan. sunden@tottori-u.ac.jp.ORCID http://orcid.org/0000-0003-0856-2940
Misaki HoriguchiLaboratory of Veterinary Pathology, Joint Department of Veterinary Medicine, Faculty of Agriculture, Tottori University, 4-101 Koyama-Minami, Tottori, 680-8553, Japan.
Hirosei SakoyaNiihama Animal Hospital, 2-1-11 Wakamizu Niihama, Ehime, 792-0017, Japan.
Mana YokogawaNiihama Animal Hospital, 2-1-11 Wakamizu Niihama, Ehime, 792-0017, Japan.
Hiroyuki InoNiihama Animal Hospital, 2-1-11 Wakamizu Niihama, Ehime, 792-0017, Japan.
Satoshi UneNeovets VR Center, 3-8-15 Nakamichi, Higashinari, Osaka, 537-0025, Japan.
Mutsumi KawataNeovets VR Center, 3-8-15 Nakamichi, Higashinari, Osaka, 537-0025, Japan.
Taisei HosoidoNeovets VR Center, 3-8-15 Nakamichi, Higashinari, Osaka, 537-0025, Japan.
Takehito MoritaLaboratory of Veterinary Pathology, Joint Department of Veterinary Medicine, Faculty of Agriculture, Tottori University, 4-101 Koyama-Minami, Tottori, 680-8553, Japan.
National Institute of Technology, Niihama College · JPTottori University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFeline leukemia virus (FeLV) is a retrovirus with global impact on the health of domestic cats and is usually examined by serology. In our daily clinical practice, we noticed that cats infected with FeLV often possess wavy whiskers (sinus hairs on the face). To investigate the relationship between wavy whiskers (WW) and FeLV infection, the association between the presence or absence of wavy changes in whiskers and serological FeLV infection was examined in a total of 358 cats including 56 cats possessing WW, using the chi-square test. The results of blood tests from 223 cases were subjected to multivariate analysis (logistic analysis). Isolated whiskers were observed under light microscopy, and upper lip tissues (proboscis) were subjected to histopathological and immunohistochemical analyses.

resultsThe prevalence of WW was significantly correlated with FeLV antigen positivity in the blood. Of 56 cases with WW, 50 (89.3%) were serologically positive for FeLV. The significant association between WW and serological FeLV positivity was also confirmed by multivariate analysis. In WW, narrowing, degeneration, and tearing of the hair medulla were observed. Mild infiltration of mononuclear cells in the tissues, but no degeneration or necrosis, was found. By immunohistochemistry, FeLV antigens (p27, gp70 and p15E) were observed in various epithelial cells including the sinus hair follicular epithelium of the whisker.

conclusionsThe data suggest that the wavy changes in whiskers, a unique and distinctive external sign on a cat's face, were associated with FeLV infection.

Indexed as

Leukemia Virus, FelineVibrissaeAnimalsCatsEpithelial CellsEpitheliumHairFeline leukemia virusFeLVPathologyWavy whisker (WW)

Identifiers

PMID36871053
PMCPMC9985215
OpenAlexW4323075325

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.