Evidence map›Paper›PMID 36871047›Full record

ArticleNature communications2023

Fibroblast growth factor 18 alleviates stress-induced pathological cardiac hypertrophy in male mice.

Gen Chen, Ning An, Jingling Shen, Huinan Chen, Yunjie Chen, Jia Sun, Zhicheng Hu, Junhui Qiu, Cheng Jin, Shengqu He and 12 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 7 institutions in 2 countries.

Gen Chen *School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, 325035, P.R. China.
Ning An *Department of Pharmacy, The Affiliated Li Huili Hospital, Ningbo University, Ningbo, 315040, P.R. China.
Jingling Shen *Institute of Life Sciences, College of Life and Environmental Sciences, Wenzhou University, Wenzhou, 325035, P.R. China.
Huinan ChenSchool of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, 325035, P.R. China.
Yunjie ChenDepartment of Pharmacy, Ningbo First Hospital, Ningbo, 315010, P.R. China.
Jia SunSchool of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, 325035, P.R. China.
Zhicheng HuOujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, P.R. China.
Junhui QiuSchool of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, 325035, P.R. China.
Cheng JinSchool of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, 325035, P.R. China.
Shengqu HeSchool of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, 325035, P.R. China.
Lin MeiDepartment of Pharmacy, Xiamen Medical College, Xiamen, 361023, PR China.
Yanru SuiSchool of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, 325035, P.R. China.
Wanqian LiPharmacy Department, Taizhou Municipal Hospital, Taizhou, 318000, P.R. China.
Peng ChenDepartment of Cardiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325027, P.R. China.
Xueqiang GuanDepartment of Cardiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325027, P.R. China.
Maoping ChuPediatric Research Institute, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325027, P.R. China.ORCID 0000-0003-0975-7176
Yang WangDepartment of Histology and Embryology, Institute of Neuroscience, Wenzhou Medical University, Wenzhou, 325035, China.
Litai JinSchool of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, 325035, P.R. China.ORCID 0000-0002-7598-5938
Kwonseop KimCollege of Pharmacy, Chonnam National University, Gwangju, 61186, Korea.
Xiaokun LiSchool of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, 325035, P.R. China. profxiaokunli@163.com.ORCID 0000-0002-7121-5768
Weitao CongSchool of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, 325035, P.R. China. cwt97126@126.com.ORCID 0000-0002-1033-291X
Xu WangSchool of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, 325035, P.R. China. wang_xu2003@163.com.ORCID 0000-0003-4781-5250
Wenzhou Medical University · CNNingbo University · CNChonnam National University · KRNingbo First Hospital · CNTaizhou Municipal Hospital · CNWenzhou University · CNXiamen Medical College

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibroblast growth factor-18 (FGF18) has diverse organ development and damage repair roles. However, its role in cardiac homeostasis following hypertrophic stimulation remains unknown. Here we investigate the regulation and function of the FGF18 in pressure overload (PO)-induced pathological cardiac hypertrophy. FGF18 heterozygous (Fgf18

Indexed as

Fibroblast Growth FactorsTandem Mass SpectrometryAnimalsCardiomegalyChromatography, LiquidMaleMiceMice, KnockoutMyocytes, Cardiacfibroblast growth factor 18Fibroblast Growth Factors

Identifiers

PMID36871047
PMCPMC9985628
OpenAlexW4323075052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.