Evidence map›Paper›PMID 36870992›Full record

ArticleMicrobial cell factories2023

Membrane-based continuous fermentation with cell recycling for propionic acid production from glycerol by Acidipropionibacterium acidipropionici.

Victor Hugo Cavero-Olguin, Tarek Dishisha, Rajni Hatti-Kaul

Open access · goldAbstract read
In one paragraph

Article in Microbial cell factories, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 3 countries.

Victor Hugo Cavero-OlguinDivision of Biotechnology, Department of Chemistry, Center for Chemistry & Chemical Engineering, Lund University, 124, 221 00, Lund, Sweden.
Tarek DishishaDepartment of Pharmaceutical Microbiology and Immunology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, 62511, Egypt.
Rajni Hatti-KaulDivision of Biotechnology, Department of Chemistry, Center for Chemistry & Chemical Engineering, Lund University, 124, 221 00, Lund, Sweden. Rajni.Hatti-Kaul@biotek.lu.se.
Lund University · SEBeni-Suef University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMicrobial production of propionic acid (PA) from renewable resources is limited by the slow growth of the producer bacteria and product-mediated inhibition. The present study evaluates high cell density continuous PA fermentation from glycerol (Gly) using Acidipropionibacterium acidipropionici DSM 4900 in a membrane-based cell recycling system. A ceramic tubular membrane filter of 0.22 μm pore size was used as the filtering device for cell recycling. The continuous fermentations were run sequentially at dilution rates of 0.05 and 0.025 1/h using varying glycerol concentrations and two different yeast extract concentrations.

resultsPA volumetric productivity of 0.98 g/L.h with a product yield of 0.38 g

conclusionsApplying the current approach for PA fermentation can overcome several limitations for process industrialization.

Indexed as

GlycerolPropionibacteriumCell MembraneFermentationPropionatesPropionibacteriaceaeGlycerolPropionatespropionic acidBiorefineryFermentationGlycerolPropionibacteriaPropionic acid

Identifiers

PMID36870992
PMCPMC9985857
OpenAlexW4323051035

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.